Dynamic Regulation of the Large Exocytotic Fusion Pore in Pancreatic Acinar Cells

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Release of secretory products during transient vesicle fusion

1993 • 582 citations

The exocytotic event in chromaffin cells revealed by patch amperometry

1997 • 555 citations

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1984 • 506 citations

Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate

1993 • 488 citations

Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability

2005 • 422 citations

High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism

1999 • 414 citations

Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells

2003 • 361 citations

DEPLETION OF VESICLES FROM FROG NEUROMUSCULAR JUNCTIONS BY PROLONGED TETANIC STIMULATION

1972 • 296 citations

Synaptotagmin Modulation of Fusion Pore Kinetics in Regulated Exocytosis of Dense-Core Vesicles

2001 • 294 citations

Simultaneous electrical and optical measurements show that membrane fusion precedes secretory granule swelling during exocytosis of beige mouse mast cells.

1987 • 280 citations

Surface dynamics in living acinar cells imaged by atomic force microscopy: Identification of plasma membrane structures involved in exocytosis

1997 • 272 citations

Properties of the fusion pore that forms during exocytosis of a mast cell secretory vesicle

1990 • 262 citations

Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis

1998 • 257 citations

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion

2003 • 225 citations

Mechanisms of Dense Core Vesicle Recapture following “Kiss and Run” (“Cavicapture”) Exocytosis in Insulin-secreting Cells

2004 • 201 citations

Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells

2002 • 189 citations

Sequential-replenishment mechanism of exocytosis in pancreatic acini

2001 • 177 citations

Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells

2004 • 176 citations

CHANGES IN THE SARCOPLASMIC RETICULUM AND TRANSVERSE TUBULAR SYSTEM OF FAST AND SLOW SKELETAL MUSCLES OF THE MOUSE DURING POSTNATAL DEVELOPMENT

1971 • 166 citations

Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size

2002 • 150 citations

Selective nucleotide-release from dense-core granules in insulin-secreting cells

2005 • 136 citations

Stabilization of Exocytosis by Dynamic F-actin Coating of Zymogen Granules in Pancreatic Acini

2004 • 135 citations

Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity

2004 • 134 citations

Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D

2000 • 134 citations

Complexin Regulates the Closure of the Fusion Pore during Regulated Vesicle Exocytosis

2002 • 127 citations

New Roles of Myosin II during Vesicle Transport and Fusion in Chromaffin Cells

2004 • 121 citations

Pancreatic β-Cells Secrete Insulin in Fast- and Slow-Release Forms

2006 • 98 citations

Fusion pore expansion is a slow, discontinuous, and Ca2+-dependent process regulating secretion from alveolar type II cells

2001 • 95 citations

Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells

2005 • 87 citations

Kiss-and-Coat and Compartment Mixing: Coupling Exocytosis to Signal Generation and Local Actin Assembly

2006 • 78 citations

The Plasma Membrane Q-SNARE Syntaxin 2 Enters the Zymogen Granule Membrane during Exocytosis in the Pancreatic Acinar Cell

2004 • 70 citations

Synchronous Exocytosis in Paramecium Cells

1987 • 69 citations

Exocytotic fusion pores exhibit semi-stable states

1993 • 69 citations

Two phases of zymogen granule lifetime in mouse pancreas: ghost granules linger after exocytosis of contents

2005 • 51 citations

THE NUMBER OF SECRETORY VESICLES REMAINS UNCHANGED FOLLOWING EXOCYTOSIS

2002 • 46 citations

Comparison of transient and successful fusion pores connecting influenza hemagglutinin expressing cells to planar membranes.

1995 • 37 citations

Lysine-fixable dye tracing of exocytosis shows F-actin coating is a step that follows granule fusion in pancreatic acinar cells

2004 • 37 citations

Retention and stimulus-dependent recycling of dense core vesicle content in neuroendocrine cells

2004 • 36 citations

Tubular system volume changes in twitch fibres from toad and rat skeletal muscle assessed by confocal microscopy

2002 • 32 citations

Synchronous exocytosis in Paramecium cells. VI. ultrastructural analysis of membrane resealing and retrieval

1985 • 31 citations

Reinternalization of secretory proteins during membrane recycling in rat pancreatic acinar cells.

1987 • 19 citations