Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Membrane Fusion and Exocytosis

1999 • 1,252 citations

SNARE-mediated membrane fusion

2001 • 1,121 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy

1997 • 850 citations

Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells

1992 • 809 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Dynamin-mediated Internalization of Caveolae

1998 • 750 citations

SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

2001 • 669 citations

Dynamin Undergoes a GTP-Dependent Conformational Change Causing Vesiculation

1998 • 665 citations

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium

1998 • 657 citations

Release of secretory products during transient vesicle fusion

1993 • 582 citations

The exocytotic event in chromaffin cells revealed by patch amperometry

1997 • 555 citations

Accessory factors in clathrin-dependent synaptic vesicle endocytosis

2000 • 513 citations

Synaptic Vesicle Endocytosis Impaired by Disruption of Dynamin-SH3 Domain Interactions

1997 • 479 citations

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

2001 • 451 citations

Kinetics and regulation of fast endocytosis at hippocampal synapses

1998 • 422 citations

High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism

1999 • 414 citations

Real-time measurement of transmitter release from single synaptic vesicles

1995 • 404 citations

Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring

1999 • 380 citations

Endocytosis and Signaling

2001 • 377 citations

Vesicle hypothesis of the release of quanta of acetylcholine.

1980 • 364 citations

Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP, and dynamin but not clathrin.

1995 • 278 citations

The SH3 Domain of Amphiphysin Binds the Proline-rich Domain of Dynamin at a Single Site That Defines a New SH3 Binding Consensus Sequence

1997 • 256 citations

Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion

1995 • 249 citations

“Kiss and run” exocytosis at hippocampal synapses

2000 • 249 citations

Dynamin at actin tails

2002 • 236 citations

Dynamin:Gtp Controls the Formation of Constricted Coated Pits, the Rate Limiting Step in Clathrin-Mediated Endocytosis

2000 • 232 citations

Characterization of the immature secretory granule, an intermediate in granule biogenesis.

1991 • 231 citations

Ca2+-Triggered Peptide Secretion in Single Cells Imaged with Green Fluorescent Protein and Evanescent-Wave Microscopy

1997 • 229 citations

The large GTPase dynamin regulates actin comet formation and movement in living cells

2002 • 224 citations

Dynamin family of mechanoenzymes

2001 • 197 citations

SNARE assembly and disassembly exhibit a pronounced hysteresis

2002 • 193 citations

Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size

2002 • 150 citations

Activity-dependent regulation of synaptic clustering in a hippocampal culture system

1999 • 136 citations

Altered Presynaptic Vesicle Release and Cycling during mGluR-Dependent LTD

2002 • 133 citations

Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells

2002 • 128 citations

SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs

2002 • 117 citations

The role of coated vesicles in recycling of synaptic vesicle membrane

1989 • 106 citations

The ATPase activity of N-ethylmaleimide-sensitive fusion protein (NSF) is regulated by soluble NSF attachment proteins.

1994 • 104 citations

A Cell-Free System for Regulated Exocytosis in Pc12 Cells

2000 • 102 citations

Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells

1997 • 75 citations

Secretion: Dense-core vesicles can kiss-and-run too

1998 • 71 citations

Relationship between NGF-mediated volume increase and “priming effect” in fast and slow reacting clones of PC12 pheochromocytoma cells

1983 • 70 citations

Synaptic Vesicles Form by Budding from Tubular Extensions of Sorting Endosomes in PC12 Cells

1999 • 62 citations

Biogenesis of Neurosecretory Vesicles

1995 • 46 citations

Sweeping Model of Dynamin Activity

2002 • 40 citations

Direct observation of membrane retrieval in chromaffin cells by capacitance measurements

2001 • 23 citations

Horseradish peroxidase uptake and crinophagy in insulin-secreting cells

1986 • 11 citations