Selective nucleotide-release from dense-core granules in insulin-secreting cells

THE GREEN FLUORESCENT PROTEIN

1998 • 5,991 citations

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

1998 • 2,538 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines.

1992 • 1,128 citations

TURNOVER OF TRANSMITTER AND SYNAPTIC VESICLES AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 835 citations

Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells

1992 • 809 citations

Release of secretory products during transient vesicle fusion

1993 • 582 citations

The exocytotic event in chromaffin cells revealed by patch amperometry

1997 • 555 citations

Currents through the fusion pore that forms during exocytosis of a secretory vesicle

1987 • 432 citations

Single synaptic vesicles fusing transiently and successively without loss of identity

2003 • 414 citations

High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism

1999 • 414 citations

Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells

2003 • 361 citations

Transmembrane Segments of Syntaxin Line the Fusion Pore of Ca ² +-Triggered Exocytosis

2004 • 341 citations

Synaptotagmin Modulation of Fusion Pore Kinetics in Regulated Exocytosis of Dense-Core Vesicles

2001 • 294 citations

Simultaneous electrical and optical measurements show that membrane fusion precedes secretory granule swelling during exocytosis of beige mouse mast cells.

1987 • 280 citations

Fusion Pore Dynamics and Insulin Granule Exocytosis in the Pancreatic Islet

2002 • 265 citations

Properties of the fusion pore that forms during exocytosis of a mast cell secretory vesicle

1990 • 262 citations

Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion

1995 • 249 citations

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells

2001 • 243 citations

VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion.

1995 • 223 citations

Delay between Fusion Pore Opening and Peptide Release from Large Dense-Core Vesicles in Neuroendocrine Cells

2002 • 208 citations

Multiple Forms of “Kiss-and-Run” Exocytosis Revealed by Evanescent Wave Microscopy

2003 • 201 citations

Mechanisms of Dense Core Vesicle Recapture following “Kiss and Run” (“Cavicapture”) Exocytosis in Insulin-secreting Cells

2004 • 201 citations

Imaging Calcium Entry Sites and Ribbon Structures in Two Presynaptic Cells

2003 • 190 citations

Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells

2002 • 189 citations

Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells

2004 • 176 citations

Regulation of dense core release from neuroendocrine cells revealed by imaging single exocytic events

1999 • 149 citations

Mucin Exocytosis

1991 • 140 citations

Simultaneous evanescent wave imaging of insulin vesicle membrane and cargo during a single exocytotic event

2000 • 132 citations

Complexin Regulates the Closure of the Fusion Pore during Regulated Vesicle Exocytosis

2002 • 127 citations

The Secretory Granule Matrix: A Fast-Acting Smart Polymer

1993 • 125 citations

Bilayers merge even when exocytosis is transient

2004 • 125 citations

Fusion pore expansion in horse eosinophils is modulated by Ca2+ and protein kinase C via distinct mechanisms

1998 • 120 citations

Glycoproteins and proteoglycans of the chromaffin granule matrix.

1982 • 116 citations

Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets.

1995 • 116 citations

Insulin secretory granule biogenesis and the proinsulin-processing endopeptidases

1994 • 103 citations

Control of neurotransmitter release by an internal gel matrix in synaptic vesicles

2003 • 102 citations

A highly Ca ²⁺ -sensitive pool of vesicles is regulated by protein kinase C in adrenal chromaffin cells

2002 • 90 citations

Release of Catecholamines and Specific Protein from Adrenal Glands

1966 • 86 citations

Characterization of ATP Transport into Chromaffin Granule Ghosts

1996 • 76 citations

Kinetics of release of serotonin from isolated secretory granules. II. Ion exchange determines the diffusivity of serotonin

1997 • 76 citations

Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X ₂ -green fluorescent protein receptors

2001 • 75 citations

Regulated Exocytosis and Kiss-and-Run of Synaptic-Like Microvesicles in INS-1 and Primary Rat β-Cells

2005 • 69 citations

A novel Ca²⁺‐dependent step in exocytosis subsequent to vesicle fusion

1995 • 69 citations

Fluorescent Cargo Proteins in Pancreatic β-Cells: Design Determines Secretion Kinetics at Exocytosis

2004 • 67 citations

Quantal Secretion from Adrenal Medulla: All-or-None Release of Storage Vesicle Content

1969 • 61 citations

Capacitance Flickers and Pseudoflickers of Small Granules, Measured in the Cell-Attached Configuration

1998 • 50 citations

Recycling of the dense-core vesicle membrane protein phogrin in Min6 β-cells

2004 • 48 citations

Temperature‐Sensitive Random Insulin Granule Diffusion is a Prerequisite for Recruiting Granules for Release

2004 • 39 citations

Exocytosis of Catecholamine (CA)-containing and CA-free Granules in Chromaffin Cells

2001 • 33 citations

Quantal analysis of 5‐hydroxytryptamine release from mouse pancreatic β‐cells

1999 • 30 citations

Catecholamines (CA) and adenosine triphosphate (ATP) are separately stored in bovine adrenal medulla, both in ionic linkage to granule sites, and not as a non‐diffusible CA‐ATP‐protein complex*

1988 • 13 citations