Two phases of zymogen granule lifetime in mouse pancreas: ghost granules linger after exocytosis of contents

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Membrane Fusion and Exocytosis

1999 • 1,252 citations

Two-Photon Imaging of Lymphocyte Motility and Antigen Response in Intact Lymph Node

2002 • 1,177 citations

Measurement of Intracellular Calcium

1999 • 751 citations

Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate

1993 • 488 citations

DYNAMIC CHANGES IN THE ULTRASTRUCTURE OF THE ACINAR CELL OF THE RAT PAROTID GLAND DURING THE SECRETORY CYCLE

1969 • 435 citations

Timing of neurotransmission at fast synapses in the mammalian brain

1996 • 432 citations

Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells

2003 • 361 citations

DEPLETION OF VESICLES FROM FROG NEUROMUSCULAR JUNCTIONS BY PROLONGED TETANIC STIMULATION

1972 • 296 citations

Fusion Pore Dynamics and Insulin Granule Exocytosis in the Pancreatic Islet

2002 • 265 citations

FINE STRUCTURAL CHANGES IN RESPONSE TO HORMONAL STIMULATION OF THE PERFUSED CANINE PANCREAS

1965 • 218 citations

Delay between Fusion Pore Opening and Peptide Release from Large Dense-Core Vesicles in Neuroendocrine Cells

2002 • 208 citations

Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells

2002 • 189 citations

Comparative biology of Ca2+-dependent exocytosis: implications of kinetic diversity for secretory function

1999 • 179 citations

Sequential-replenishment mechanism of exocytosis in pancreatic acini

2001 • 177 citations

Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size

2002 • 150 citations

Regulation of dense core release from neuroendocrine cells revealed by imaging single exocytic events

1999 • 149 citations

The effects of pH and temperature on fluorescent calcium indicators as determined with Chelex-100 and EDTA buffer systems

1990 • 139 citations

Stabilization of Exocytosis by Dynamic F-actin Coating of Zymogen Granules in Pancreatic Acini

2004 • 135 citations

Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity

2004 • 134 citations

Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D

2000 • 134 citations

Simultaneous evanescent wave imaging of insulin vesicle membrane and cargo during a single exocytotic event

2000 • 132 citations

Construction of a two-photon microscope for video-rate Ca2+ imaging

2001 • 124 citations

Synaptic vesicles: is kissing a matter of competence?

2001 • 120 citations

Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane

2001 • 96 citations

Recombinant Scinderin Enhances Exocytosis, an Effect Blocked by Two Scinderin-Derived Actin-Binding Peptides and PIP2

1996 • 80 citations

Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic β-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy

2002 • 74 citations

Compound Exocytosis and Cumulative Fusion in Eosinophils

2003 • 73 citations

Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane

2001 • 44 citations

Lysine-fixable dye tracing of exocytosis shows F-actin coating is a step that follows granule fusion in pancreatic acinar cells

2004 • 37 citations

Optical measurement of stimulus-evoked membrane dynamics in single pancreatic acinar cells

1998 • 29 citations

Exocytosis and movement of zymogen granules observed by VEC-DIC microscopy in the pancreatic tissue en bloc

2000 • 26 citations

Zymogen granule acidity is not required for stimulated pancreatic protein secretion

1987 • 17 citations