Stabilization of Exocytosis by Dynamic F-actin Coating of Zymogen Granules in Pancreatic Acini

Two-Photon Laser Scanning Fluorescence Microscopy

1990 • 9,129 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho GTPases in cell biology

2002 • 4,662 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Small GTP-Binding Proteins

2001 • 2,449 citations

Effects of cytochalasin and phalloidin on actin.

1987 • 1,989 citations

Inhibition of actin polymerization by latrunculin A

1987 • 813 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

Phosphoinositide Regulation of the Actin Cytoskeleton

2003 • 644 citations

Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue

1977 • 571 citations

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

1980 • 444 citations

Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells.

1995 • 436 citations

Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas

1990 • 393 citations

Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion

1972 • 360 citations

Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells

2000 • 353 citations

Fusion Pore Dynamics and Insulin Granule Exocytosis in the Pancreatic Islet

2002 • 265 citations

FINE STRUCTURAL CHANGES IN RESPONSE TO HORMONAL STIMULATION OF THE PERFUSED CANINE PANCREAS

1965 • 218 citations

Actin-based motility: stop and go with Ena/VASP proteins

2001 • 207 citations

Is an elevated concentration of acinar cytosolic free ionised calcium the trigger for acute pancreatitis?

1995 • 183 citations

Sequential-replenishment mechanism of exocytosis in pancreatic acini

2001 • 177 citations

Actin and the agile spine: how and why do dendritic spines dance?

2000 • 172 citations

A Role for the p38 Mitogen-activated Protein Kinase/Hsp 27 Pathway in Cholecystokinin-induced Changes in the Actin Cytoskeleton in Rat Pancreatic Acini

1998 • 160 citations

Micromolar and submicromolar Ca2+ spikes regulating distinct cellular functions in pancreatic acinar cells

1997 • 155 citations

Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs

2003 • 148 citations

Functional comparison of villin and gelsolin. Effects of Ca2+, KCl, and polyphosphoinositides.

1988 • 145 citations

Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D

2000 • 134 citations

Presence of Cathepsin B in the Human Pancreatic Secretory Pathway and Its Role in Trypsinogen Activation during Hereditary Pancreatitis

2002 • 123 citations

Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze-fracture study.

1976 • 122 citations

Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell.

1990 • 117 citations

Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogue stimulation

1987 • 117 citations

Crossroads on Cytoskeletal Highways

1999 • 117 citations

Distribution of actin and the actin-associated proteins myosin, tropomyosin, alpha-actinin, vinculin, and villin in rat and bovine exocrine glands.

1983 • 114 citations

Sequential exocytosis of insulin granules is associated with redistribution of SNAP25

2004 • 109 citations

Acute Pancreatitis. Diagnosis and Therapy

1994 • 108 citations

An actin barrier to resealing

2001 • 105 citations

Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane

2001 • 96 citations

The Mammalian Sec6/8 Complex Interacts with Ca2+ Signaling Complexes and Regulates Their Activity

2000 • 93 citations

Role of Actin in Regulated Exocytosis and Compensatory Membrane Retrieval: Insights from an Old Acquaintance

1999 • 86 citations

Dynamic changes in chromaffin cell cytoskeleton as prelude to exocytosis

1992 • 83 citations

Early events in acute pancreatitis

1999 • 82 citations

Cholecystokinin Activates a Variety of Intracellular Signal Transduction Mechanisms in Rodent Pancreatic Acinar Cells

2002 • 77 citations

Acute pancreatitis : diagnosis and therapy

1994 • 68 citations

[22] Preparation of native and recombinant Clostridium botulinum C3 ADP-ribosyltransferase and identification of Rho proteins by ADP-ribosylation

1995 • 57 citations

Effects of high concentrations of secretagogues on the morphology and secretory activity of the pancreas: A role for microfilaments

1982 • 52 citations

The effect of denervation on the distribution of the polymorphic forms of troponin components in fast and slow muscles of the adult rat

1982 • 43 citations

Agonist-induced changes in cell shape during regulated secretion in rat pancreatic acini

2000 • 42 citations

Lateral diffusion of luminal membrane components during secretion in parotid acinar cells of the rat

1990 • 2 citations