Regulatory T Cells and T Cell Depletion

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 • 2,825 citations

CD4+CD25high Regulatory Cells in Human Peripheral Blood

2001 • 1,882 citations

Regulatory T Cells

2000 • 1,827 citations

Improved Graft Survival after Renal Transplantation in the United States, 1988 to 1996

2000 • 1,803 citations

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

2006 • 1,135 citations

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

2005 • 1,090 citations

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Tolerance, not immunity, crucially depends on IL-2

2004 • 826 citations

CD4 Regulatory T Cells Prevent Lethal Autoimmunity in IL-2Rβ-Deficient Mice

2002 • 783 citations

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

2006 • 497 citations

Immunocompetent T-Cells with a Memory-Like Phenotype are the Dominant Cell Type Following Antibody-Mediated T-Cell Depletion

2005 • 459 citations

Homeostatic proliferation is a barrier to transplantation tolerance

2003 • 403 citations

Molecular Mechanisms Underlying FOXP3 Induction in Human T Cells

2006 • 394 citations

Campath-1H Induction Plus Rapamycin Monotherapy for Renal Transplantation: Results of a Pilot Study

2003 • 379 citations

Organ transplantation—how much of the promise has been realized?

2005 • 378 citations

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

2005 • 378 citations

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

2004 • 373 citations

A Novel Mechanism of Action for Anti-Thymocyte Globulin

2006 • 365 citations

Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate.

1995 • 365 citations

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis

2005 • 289 citations

MECHANISMS INVOLVED IN ANTITHYMOCYTE GLOBULIN IMMUNOSUPPRESSIVE ACTIVITY IN A NONHUMAN PRIMATE MODEL 1

2001 • 280 citations

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location.

1993 • 264 citations

Calcineurin Inhibitors, but not Rapamycin, Reduce Percentages of CD4+CD25+FOXP3+ Regulatory T Cells in Renal Transplant Recipients

2006 • 245 citations

Foxp3⁺CD25^–CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

2005 • 228 citations

Induction of Fas (Apo-1, CD95)-Mediated Apoptosis of Activated Lymphocytes by Polyclonal Antithymocyte Globulins

1998 • 212 citations

Global and Specific Translational Control by Rapamycin in T Cells Uncovered by Microarrays and Proteomics

2002 • 192 citations

Rapamycin-Mediated Enrichment of T Cells with Regulatory Activity in Stimulated CD4+ T Cell Cultures Is Not Due to the Selective Expansion of Naturally Occurring Regulatory T Cells but to the Induction of Regulatory Functions in Conventional CD4+ T Cells

2006 • 189 citations

Alemtuzumab Induction and Prednisone‐Free Maintenance Immunotherapy in Kidney Transplantation: Comparison with Basiliximab Induction—Long‐Term Results

2005 • 186 citations

The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

2003 • 180 citations

Effector mechanisms in transplant rejection

2003 • 180 citations

The Immunological Effects of Extracorporeal Photopheresis Unraveled: Induction of Tolerogenic Dendritic Cells In Vitro and Regulatory T Cells In Vivo

2005 • 178 citations

Infectious tolerance and the long‐term acceptance of transplanted tissue

2006 • 168 citations

Mechanism of action of rapamycin: New insights into the regulation of G1-phase progression in eukaryotic cells

1995 • 166 citations

DAILY RENAL HYPOPERFUSION INDUCED BY CYCLOSPORINE IN PATIENTS WITH RENAL TRANSPLANTATION

1992 • 165 citations

Alemtuzumab (Campath-1H): A Systematic Review in Organ Transplantation

2006 • 161 citations

Specificity of CD4+CD25+ Regulatory T Cell Function in Alloimmunity

2006 • 121 citations

Randomized Trial of Alemtuzumab for Prevention of Graft Rejection and Preservation of Renal Function after Kidney Transplantation1

2005 • 108 citations

CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody

2006 • 95 citations

Everolimus and Basiliximab Permit Suppression by Human CD4+CD25+ Cells in vitro

2005 • 94 citations

Recipient Memory-Like Lymphocytes Remain Unresponsive to Graft Antigens After CAMPATH-1H Induction with Reduced Maintenance Immunosuppression

2006 • 78 citations

The Generation of CD25+CD4+ Regulatory T Cells That Prevent Allograft Rejection Does Not Compromise Immunity to a Viral Pathogen

2005 • 73 citations

Therapeutic Drug Monitoring of Sirolimus: Effect of Concomitant Immunosuppressive Therapy and Optimization of Drug Dosing

2004 • 64 citations

DEPLETING ANTI-CD4 MONOCLONAL ANTIBODY CURES NEW-ONSET DIABETES, PREVENTS RECURRENT AUTOIMMUNE DIABETES, AND DELAYS ALLOGRAFT REJECTION IN NONOBESE DIABETIC MICE1

2004 • 61 citations

Tolerance Assays: Measuring the Unknown

2006 • 45 citations

Restriction of De Novo Nucleotide Biosynthesis Interferes with Clonal Expansion and Differentiation into Effector and Memory CD8 T Cells

2004 • 38 citations

Immunophenotypic Analysis of Cellular Infiltrate of Renal Allograft Biopsies in Patients with Acute Rejection after Induction with Alemtuzumab (Campath-1H)

2006 • 34 citations

CD25+Foxp3+ Regulatory T Cells Facilitate CD4+ T Cell Clonal Anergy Induction during the Recovery from Lymphopenia

2006 • 33 citations

Reversibility with Interleukin-2 Suggests that T Cell Anergy Contributes to Donor-Specific Hyporesponsiveness in Renal Transplant Patients

2002 • 33 citations

Induction of immunological tolerance using monoclonal antibodies: Applications to organ transplantation and autoimmune disease

2006 • 7 citations

Deleted Work

1955 • 0 citations