CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 • 2,825 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

Regulatory T Cells

2000 • 1,827 citations

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

1995 • 1,212 citations

Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

2002 • 1,189 citations

The Technique of Free Skin Grafting in Mammals

1951 • 760 citations

Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo

2001 • 658 citations

OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

2001 • 638 citations

TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

2003 • 595 citations

Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys

1995 • 552 citations

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.

1997 • 489 citations

Immunocompetent T-Cells with a Memory-Like Phenotype are the Dominant Cell Type Following Antibody-Mediated T-Cell Depletion

2005 • 459 citations

RESULTS FROM A HUMAN RENAL ALLOGRAFT TOLERANCE TRIAL EVALUATING THE HUMANIZED CD52-SPECIFIC MONOCLONAL ANTIBODY ALEMTUZUMAB (CAMPATH-1H)

2003 • 432 citations

Homeostatic proliferation is a barrier to transplantation tolerance

2003 • 403 citations

Campath-1H Induction Plus Rapamycin Monotherapy for Renal Transplantation: Results of a Pilot Study

2003 • 379 citations

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

2004 • 373 citations

Transplantation of Cultured Islets from Two-Layer Preserved Pancreases in Type 1 Diabetes with Anti-CD3 Antibody

2004 • 367 citations

4-1BB Promotes the Survival of CD8+ T Lymphocytes by Increasing Expression of Bcl-xL and Bfl-1

2002 • 358 citations

LONG-TERM RESULTS OF A CONTROLLED PROSPECTIVE STUDY WITH TRANSFUSION OF DONOR-SPECIFIC BONE MARROW IN 57 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

1991 • 285 citations

MECHANISMS INVOLVED IN ANTITHYMOCYTE GLOBULIN IMMUNOSUPPRESSIVE ACTIVITY IN A NONHUMAN PRIMATE MODEL 1

2001 • 280 citations

Foxp3⁺CD25^–CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

2005 • 228 citations

Induction of Fas (Apo-1, CD95)-Mediated Apoptosis of Activated Lymphocytes by Polyclonal Antithymocyte Globulins

1998 • 212 citations

ANTIBODIES AGAINST FUNCTIONAL LEUKOCYTE SURFACE MOLECULES IN POLYCLONAL ANTILYMPHOCYTE AND ANTITHYMOCYTE GLOBULINS

1991 • 203 citations

Differential response of murine CD4⁺CD25⁺ and CD4⁺CD25^– T cells to dexamethasone‐induced cell death

2004 • 186 citations

A COMPREHENSIVE DEFINITION OF THE MAJOR ANTIBODY SPECIFICITIES IN POLYCLONAL RABBIT ANTITHYMOCYTE GLOBULIN1

1994 • 167 citations

Cure of Overt Diabetes in NOD Mice by Transient Treatment With Anti-Lymphocyte Serum and Exendin-4

2004 • 162 citations

Fibroblast Growth Factor-2 Induces Translational Regulation of Bcl-XL and Bcl-2 via a MEK-dependent Pathway

2002 • 143 citations

Long-term abrogation of autoimmune diabetes in nonobese diabetic mice by immunotherapy with anti-lymphocyte serum.

1992 • 103 citations

Renal allograft tolerance induced with ATG and donor bone marrow in outbred rhesus monkeys.

1983 • 90 citations

Use of homozygous allogeneic bone marrow for induction of tolerance with antilymphocyte serum: dose and timing.

1971 • 86 citations

RENAL ALLOGRAFT TOLERANCE INDUCED WITH ATG AND DONOR BONE MARROW IN OUTBRED RHESUS MONKEYS

1983 • 80 citations

Modulation of apoptosis-associated genes bcl-2, bcl-x, and bax during rat liver regeneration.

1996 • 69 citations

Specific unresponsiveness to skin allografts in anti-lymphocyte serum-treated, marrow-injected mice: participation of donor marrow-derived suppressor T cells.

1981 • 67 citations

DEVELOPMENT OF SUPPRESSOR T CELLS BY ANTILYMPHOCYTE SERUM TREATMENT IN MICE

1982 • 33 citations

DETERMINATION OF AN IMPROVED SIROLIMUS (RAPAMYCIN)-BASED REGIMEN FOR INDUCTION OF ALLOGRAFT TOLERANCE IN MICE TREATED WITH ANTILYMPHOCYTE SERUM AND DONOR-SPECIFIC BONE MARROW1

1998 • 27 citations

Immunologic mechanisms in tolerance produced in mice with nonradiation-based lymphoablation and donor-specific bone marrow

2002 • 25 citations

Effect of STZ Administration on Islet Isograft and Allograft Survival in NOD Mice

1993 • 16 citations

Induction of Fas (Apo-1, CD95)-Mediated Apoptosis of Activated Lymphocytes by Polyclonal Antithymocyte Globulins

1998 • 13 citations

Effect of STZ administration on islet isograft and allograft survival in NOD mice

1993 • 3 citations