AtXRN4 Degrades mRNA in Arabidopsis and Its Substrates Include Selected miRNA Targets

MicroRNAs

2004 • 33,206 citations

RNA interference

2002 • 3,369 citations

Prediction of Plant MicroRNA Targets

2002 • 2,239 citations

Regulation of Flowering Time and Floral Organ Identity by a MicroRNA and Its APETALA2-Like Target Genes

2003 • 1,833 citations

MicroRNAs in plants

2002 • 1,791 citations

Role of MicroRNAs in Plant and Animal Development

2003 • 1,765 citations

Control of leaf morphogenesis by microRNAs

2003 • 1,756 citations

A MicroRNA as a Translational Repressor of APETALA2 in Arabidopsis Flower Development

2003 • 1,694 citations

MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 • 1,680 citations

Cleavage of Scarecrow-like mRNA Targets Directed by a Class of Arabidopsis miRNA

2002 • 1,569 citations

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

2003 • 1,323 citations

CARPEL FACTORY, a Dicer Homolog, and HEN1, a Novel Protein, Act in microRNA Metabolism in Arabidopsis thaliana

2002 • 1,243 citations

Radial Patterning of Arabidopsis Shoots by Class III HD-ZIP and KANADI Genes

2003 • 1,091 citations

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

2002 • 1,081 citations

A biochemical framework for RNA silencing in plants

2003 • 985 citations

A High-Throughput Arabidopsis Reverse Genetics System

2002 • 962 citations

P1/HC-Pro, a Viral Suppressor of RNA Silencing, Interferes with Arabidopsis Development and miRNA Function

2003 • 953 citations

The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases

1997 • 939 citations

Endogenous and Silencing-Associated Small RNAs in Plants[W]

2002 • 908 citations

The enzymes and control of eukaryotic mRNA turnover

2004 • 793 citations

T-DNA as an Insertional Mutagen in Arabidopsis

1999 • 726 citations

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

1993 • 660 citations

Genes Galore: A Summary of Methods for Accessing Results from Large-Scale Partial Sequencing of Anonymous Arabidopsis cDNA Clones

1994 • 639 citations

The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

1998 • 632 citations

The Nuclear dsRNA Binding Protein HYL1 Is Required for MicroRNA Accumulation and Plant Development, but Not Posttranscriptional Transgene Silencing

2004 • 514 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

RNAi: nature abhors a double-strand

2002 • 509 citations

Spatially restricted microRNA directs leaf polarity through ARGONAUTE1

2004 • 498 citations

Genome-Wide Analysis of mRNAs Regulated by the Nonsense-Mediated and 5′ to 3′ mRNA Decay Pathways in Yeast

2003 • 402 citations

Premature translational termination triggers mRNA decapping

1994 • 399 citations

The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci

2002 • 387 citations

Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure.

1993 • 378 citations

The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements

2002 • 369 citations

Nonsense-Mediated mRNA Decay in Mammalian Cells Involves Decapping, Deadenylating, and Exonucleolytic Activities

2003 • 365 citations

A Mouse Cytoplasmic Exoribonuclease (mXRN1p) with Preference for G4 Tetraplex Substrates

1997 • 341 citations

Turnover Mechanisms of the Stable Yeast PGK1 mRNA

1995 • 341 citations

RNA-Mediated RNA Degradation and Chalcone Synthase A Silencing in Petunia

1997 • 308 citations

Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening.

1994 • 290 citations

mRNA stability in eukaryotes

2000 • 278 citations

Functional Link between the Mammalian Exosome and mRNA Decapping

2001 • 254 citations

The Exosome

1999 • 215 citations

DST sequences, highly conserved among plant SAUR genes, target reporter transcripts for rapid decay in tobacco.

1993 • 208 citations

Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: Rapid decay is associated with a group of touch- and specific clock-controlled genes

2002 • 206 citations

Evidence for Autoregulation of Cystathionine γ-Synthase mRNA Stability in Arabidopsis

1999 • 183 citations

Novel features of the XRN-family in Arabidopsis : Evidence that AtXRN4, one of several orthologs of nuclear Xrn2p/Rat1p, functions in the cytoplasm

2000 • 160 citations

Regulation of S-Like Ribonuclease Levels in Arabidopsis. Antisense Inhibition of RNS1 orRNS2 Elevates Anthocyanin Accumulation1

1999 • 157 citations

mRNA degradation machines in eukaryotic cells

2002 • 150 citations

Characterization of cis-Acting Sequences and Decay Intermediates Involved in Nonsense-Mediated mRNA Turnover

1995 • 146 citations

Premature nonsense codons decrease the stability of phytohemagglutinin mRNA in a position‐dependent manner

1996 • 115 citations

Nonsense-Mediated Decay of MutantwaxymRNA in Rice

2001 • 97 citations

cDNAマイクロアレイ解析によるシロイヌナズナにおける不安定転写産物の同定 迅速な崩壊は接触‐および特異的時計調節遺伝子と関連している

2002 • 84 citations

Why do miRNAs live in the miRNP?

2002 • 83 citations

The 5′–3′ exoribonuclease xrn-1 is essential for ventral epithelial enclosure during C. elegans embryogenesis

2003 • 58 citations

Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae

1998 • 57 citations

Identification and developmental expression of a 5′–3′ exoribonuclease from Drosophila melanogaster

1998 • 51 citations

Oat phytochrome A mRNA degradation appears to occur via two distinct pathways.

1994 • 46 citations

Premature termination codons destabilize ferredoxin‐1 mRNA when ferredoxin‐1 is translated

2000 • 37 citations

Degradation of the Soybean Ribulose-1,5-Bisphosphate Carboxylase Small-Subunit mRNA, SRS4, Initiates with Endonucleolytic Cleavage

1995 • 22 citations

Evidence for a 5′ → 3′ direction of hydrolysis by a 5′ mononucleotide-producing exoribonuclease from Saccharomyces cerevisiae

1979 • 16 citations

Analysis of XRN Orthologs by Complementation of Yeast Mutants and Localization of XRN–GFP Fusion Proteins

2001 • 10 citations

Deleted Work

1955 • 0 citations