Back to search

Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening.

Data up to Jan 2025

Published1994
Citations290
References59

Total Citations Per Year

Abstract

References (59)

Molecular cloning: A laboratory manual

1990 • 85,659 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Messenger RNA degradation in eukaryotes

1993 • 858 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

1989 • 561 citations

Identification of an AUUUA-Specific Messenger RNA Binding Protein

1989 • 515 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1989 • 355 citations

Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA.

1989 • 334 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

An inducible cytoplasmic factor (AU-B) binds selectively to AUUUA multimers in the 3' untranslated region of lymphokine mRNA.

1991 • 293 citations

A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs.

1991 • 268 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

1989 • 244 citations

GM-CSF and oncogene mRNA stabilities are independently regulated in trans in a mouse monocytic tumor

1988 • 227 citations

Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast

1992 • 212 citations

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

1983 • 190 citations

Function of plastid mRNA 3′ inverted repeats

1989 • 166 citations

Regulation of Interaction of the Iron-Responsive Element Binding Protein with Iron-Responsive RNA Elements

1989 • 164 citations

The role of poly(A) in the translation and stability of mRNA

1990 • 154 citations

3'-UTR-dependent deadenylation by the yeast poly(A) nuclease.

1992 • 140 citations

U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation.

1992 • 135 citations

Iron-Dependent Regulation of Ferritin and Transferrin Receptor Expression by the Iron-Responsive Element Binding Protein

1992 • 132 citations

Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.

1991 • 127 citations

An A+U-Rich Element RNA-Binding Factor Regulates c-myc mRNA Stability In Vitro

1991 • 121 citations

Nonsense Codons in Human β-Globin mRNA Result in the Production of mRNA Degradation Products

1992 • 118 citations

Degradation of apolipoprotein II mRNA occurs via endonucleolytic cleavage at 5′-AAU-3′/5′-UAA-3′ elements in single-stranded loop domains of the 3′-noncoding region

1989 • 118 citations

The interaction between the iron-responsive element binding protein and its cognate RNA is highly dependent upon both RNA sequence and structure

1993 • 108 citations

Poly(A) Tail Shortening Is the Translation-Dependent Step in c-myc mRNA Degradation

1990 • 100 citations

Sequence-specific endonucleolytic cleavage and protection of mRNA in Xenopus and Drosophila.

1993 • 99 citations

[17] A guide for probing native small nuclear RNA and ribonucleoprotein structures

1989 • 98 citations

Histone mRNA Degradation In Vivo: the First Detectable Step Occurs at or near the 3′ Terminus

1986 • 98 citations

The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region.

1992 • 96 citations

Two genetic loci participate in the regulation by iron of the gene for the human transferrin receptor.

1988 • 91 citations

Processing of 9E3 mRNA and regulation of its stability in normal and Rous sarcoma virus-transformed cells.

1989 • 86 citations

Posttranscriptional Stabilization of c-fms mRNA by a Labile Protein during Human Monocytic Differentiation

1989 • 85 citations

A 32-Kilodalton Protein Binds to AU-Rich Domains in the 3′ Untranslated Regions of Rapidly Degraded mRNAs

1991 • 81 citations

The Regulatory Function of Poly(A) and Adjacent 3' Sequences in Translated RNA

1982 • 80 citations

Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes.

1990 • 75 citations

An Inducible Cytoplasmic Factor (AU-B) Binds Selectively to AUUUA Multimers in the 3′ Untranslated Region of Lymphokine mRNA

1991 • 74 citations

Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.

1992 • 72 citations

Poly(A) Shortening and Degradation of the 3′ A+U-Rich Sequences of Human c-myc mRNA in a Cell-Free System

1988 • 71 citations

Removal of a 3′ non-coding sequence is an initial step in degradation of groα mRNA and is regulated by interleukin-1

1992 • 64 citations

Control of messenger RNA stability

1994 • 61 citations

Specific endonucleolytic cleavage of IGF-II mRNAs

1991 • 52 citations

Characterization of Rat Transferrin Receptor cDNA: The Regulation of Transferrin Receptor mRNA in Testes and in Sertoli Cells in Culture

1990 • 49 citations

Expression of Madin-Darby canine kidney cell Na(+)-and Cl(-)-dependent taurine transporter in Xenopus laevis oocytes

1991 • 48 citations

U-Rich Sequence-Binding Proteins (URBPs) Interacting with a 20-Nucleotide U-Rich Sequence in the 3′ Untranslated Region of c-fos mRNA May Be Involved in the First Step of c-fos mRNA Degradation

1992 • 35 citations

The Rate-Limiting Step in Yeast PGK1 mRNA Degradation Is an Endonucleolytic Cleavage in the 3′-Terminal Part of the Coding Region

1992 • 28 citations

An estrogen-dependent polysomal protein binds to the 5′ untranslated region of the chicken vitellogenin mRNA

1991 • 26 citations

Processing of 9E3 mRNA and Regulation of Its Stability in Normal and Rous Sarcoma Virus-Transformed Cells

1989 • 21 citations

Accelerated poly(A) loss on α-tubulin mRNAs during protein synthesis inhibition in Chlamydomonas

1989 • 17 citations

The secondary structure of the regulatory region of the transferrin receptor mRNA deduced by enzymatic cleavage.

1992 • 14 citations

Why, when and how does the poly(A) tail shorten during mRNA translation?

1993 • 8 citations

Studies on Transferrin Receptor Expression in Mouse Plasmacytoma Cells

1986 • 3 citations

Cited By (0)

No citing papers found in database

Evidence that the pathway of transferrin receptor mRNA degradation involves an… (1994) – The EMBO Journal | Metascience Observatory Explorer