ZDS1 and ZDS2, Genes Whose Products May Regulate Cdc42p in Saccharomyces cerevisiae

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Methods in yeast genetics

1979 • 7,824 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Predicting Coiled Coils from Protein Sequences

1991 • 3,977 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Tmbase-A database of membrane spanning protein segments

1993 • 2,294 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Genetic Control of the Cell Division Cycle in Yeast

1974 • 1,588 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1986 • 1,399 citations

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

A simple and efficient method for direct gene deletion inSaccharomyces cerevisiae

1993 • 1,256 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G ₁

1995 • 1,142 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Origins of Cell Polarity

1996 • 1,024 citations

MAP kinase pathways in yeast: For mating and more

1995 • 1,009 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.

1984 • 838 citations

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

1984 • 827 citations

Reserve carbohydrate metabolism in Saccharomyces cerevisiae: responses to nutrient limitation

1980 • 807 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth.

1994 • 616 citations

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

1990 • 605 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

The Saccharomyces cerevisiae Cell Cycle

1981 • 539 citations

Chapter 19 Fluorescence Microscopy Methods for Yeast

1989 • 528 citations

The septins: roles in cytokinesis and other processes

1996 • 502 citations

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

1994 • 499 citations

Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.

1989 • 406 citations

GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more

1995 • 394 citations

Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.

1994 • 392 citations

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42.

1995 • 386 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

Methods in enzymology vol 194 guide to yeast genetics and molecular biology

1991 • 359 citations

Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

1995 • 357 citations

Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: localization of the CDC3 gene product and the timing of events at the budding site.

1991 • 342 citations

The YDp plasmids: A uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae

1991 • 342 citations

Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade.

1994 • 329 citations

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

1993 • 319 citations

Cooperative interaction of S. pombe proteins required for mating and morphogenesis

1994 • 303 citations

Vectors for the inducible overexpression of glutathione S‐transferase fusion proteins in yeast

1993 • 284 citations

Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.

1994 • 283 citations

A cell cycle checkpoint monitors cell morphogenesis in budding yeast.

1995 • 267 citations

Roles of the CDC24 gene product in cellular morphogenesis during the Saccharomyces cerevisiae cell cycle.

1981 • 264 citations

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity.

1993 • 256 citations

[8] Putting the HO gene to work: Practical uses for mating-type switching

1991 • 254 citations

Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs.

1993 • 251 citations

GAPs for rho-related GTPases

1994 • 248 citations

Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module.

1994 • 243 citations

The proliferation of MAP kinase signaling pathways in yeast

1995 • 243 citations

Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe.

1994 • 217 citations

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway

1995 • 209 citations

Mutational analysis of CDC42Sc, a Saccharomyces cerevisiae gene that encodes a putative GTP-binding protein involved in the control of cell polarity.

1991 • 204 citations

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

1990 • 204 citations

Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: Localization of the CDC11 gene product and the timing of events at the budding site

1991 • 197 citations

Pheromone Signalling in Saccharomyces cerevisiae Requires the Small GTP-Binding Protein Cdc42p and Its Activator CDC24

1995 • 192 citations

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

1995 • 190 citations

Establishment of Cell Polarity in Yeast

1995 • 176 citations

Rho-related proteins: actin cytoskeleton and cell cycle

1995 • 176 citations

Association of the Yeast Pheromone Response G Protein βγ Subunits with the Map Kinase Scaffold Ste5p

1995 • 173 citations

Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42.

1990 • 172 citations

Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe.

1995 • 170 citations

A GDP Dissociation Inhibitor That Serves as a GTPase Inhibitor for the Ras-Like Protein CDC42Hs

1992 • 164 citations

Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast.

1995 • 158 citations

Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.

1995 • 158 citations

Transient G1 arrest of S. cerevisiae cells of mating type α by a factor produced by cells of mating type a

1974 • 156 citations

Regulation of mating in the cell cycle of Saccharomyces cerevisiae.

1977 • 156 citations

A Mutant of Yeast Defective in Cellular Morphogenesis

1978 • 155 citations

Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs

1996 • 141 citations

Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.

1995 • 134 citations

Mutations in elongation factor EF-1 alpha affect the frequency of frameshifting and amino acid misincorporation in Saccharomyces cerevisiae.

1988 • 125 citations

A novel role for RhoGDI as an inhibitor of GAP proteins.

1993 • 117 citations

[22] Propagation and expression of cloned genes in yeast: 2-μm circle-based vectors

1990 • 111 citations

Chapter 7 Methods for Monitoring the Growth of Yeast Cultures and for Dealing with the Clumping Problem

1975 • 98 citations

Calcium-sensitive cls4 mutant of Saccharomyces cerevisiae with a defect in bud formation

1986 • 93 citations

Molecular cloning and characterization of yeast rho GDP dissociation inhibitor.

1994 • 86 citations

Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

1993 • 81 citations

Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: isolation and characterization of the CDC24 gene and adjacent regions of the chromosome.

1986 • 74 citations

The CDC42 homologue from Caenorhabditis elegans. Complementation of yeast mutation

1993 • 61 citations

Preface

1991 • 59 citations

Cell polarization directed by extracellular cues in yeast.

1994 • 57 citations

Mutations in the Homologous ZDS1 and ZDS2 Genes Affect Cell Cycle Progression

1996 • 53 citations

Guidebook to the small GTPases

1996 • 41 citations

Genetic analysis of Saccharomyces cerevisiae chromosome I: on the role of mutagen specificity in delimiting the set of genes identifiable using temperature-sensitive-lethal mutations.

1991 • 35 citations

A DBL-homologous region of the yeast gene product is important for Ca2+-modulated bud assembly

1991 • 33 citations

Multicopy suppressors of temperature-sensitive mutations of yeast mRNA capping enzyme.

1996 • 17 citations