Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

The E2F transcription factor is a cellular target for the RB protein

1991 • 1,461 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1989 • 990 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

1991 • 446 citations

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

1991 • 435 citations

The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

1991 • 420 citations

A new group of potent inducers of differentiation in murine erythroleukemia cells.

1976 • 379 citations

Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis

1976 • 374 citations

Cloning of cDNAs for cellular proteins that bind to the retinoblastoma gene product

1991 • 334 citations

G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

1991 • 319 citations

Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation.

1988 • 314 citations

Negative regulation of human c-fos expression by thes retinoblastoma gene product

1990 • 298 citations

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.

1990 • 253 citations

Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein.

1989 • 248 citations

Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division.

1986 • 199 citations

Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.

1977 • 193 citations

Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

1990 • 149 citations

Transient inhibition of initiation of S-phase associated with dimethyl sulfoxide induction of murine erythroleukemia cells to erythroid differentiation.

1977 • 124 citations

RB and the cell cycle: Entrance or exit?

1989 • 93 citations

[22] Isolation and analysis of nuclear RNA

1987 • 91 citations

Inducer-mediated commitment of murine erythroleukemia cells to differentiation: a multistep process.

1982 • 89 citations

Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells.

1990 • 79 citations

Gene expression in murine erythroleukemia cells

1984 • 78 citations

Increased retinoblastoma gene expression is associated with late stages of differentiation in many different cell types.

1990 • 76 citations

Expression of the c-myb and c-myc genes is regulated independently in differentiating mouse erythroleukemia cells by common processes of premature transcription arrest and increased mRNA turnover.

1988 • 68 citations

Murine erythroleukemia cell differentiation: relationship of globin gene expression and of prolongation of G1 to inducer effects during G1/early S.

1979 • 64 citations

Modulation of the c-myb, c-myc and p53 mRNA and protein levels during induced murine erythroleukemia cell differentiation.

1989 • 57 citations

Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.

1990 • 52 citations

The induction of Friend erythroleukaemia differentiation is markedly affected by expression of a transfected c-myb cDNA.

1988 • 43 citations

Characteristics of erythroleukemia cells selected for vincristine resistance that have accelerated inducer-mediated differentiation.

1991 • 14 citations