The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

1990 • 9,690 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Promoter-specific activation of RNA polymerase II transcription by Sp1

1986 • 1,054 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells

1988 • 832 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene

1990 • 606 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

1990 • 543 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.

1990 • 478 citations

HBV X Protein Alters the DNA Binding Specificity of CREB and ATF-2 by Protein-Protein Interactions

1991 • 457 citations

Point Mutational Inactivation of the Retinoblastoma Antioncogene

1989 • 427 citations

Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: A novel mechanism for E1A trans-activation

1990 • 358 citations

The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.

1990 • 327 citations

The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

1989 • 307 citations

Negative regulation of human c-fos expression by thes retinoblastoma gene product

1990 • 298 citations

Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein

1990 • 295 citations

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.

1987 • 290 citations

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

1989 • 283 citations

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway.

1990 • 253 citations

An N-Terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110 and a second cellular protein, p120

1989 • 235 citations

Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen.

1990 • 204 citations

Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product.

1990 • 197 citations

Whole genome PCR: application to the identification of sequences bound by gene regulatory protein

1989 • 187 citations

C-terminal truncation of the retinoblastoma gene product leads to functional inactivation.

1990 • 170 citations

Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene.

1991 • 159 citations

A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product

1991 • 153 citations

Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complex.

1987 • 140 citations

Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein.

1991 • 113 citations

Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein.

1990 • 87 citations

Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.

1990 • 52 citations

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells

1990 • 45 citations