Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1

A simplified system for generating recombinant adenoviruses

1998 • 3,179 citations

The DNA damage response: putting checkpoints in perspective

2000 • 3,147 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

1998 • 1,734 citations

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

2000 • 1,236 citations

E2F integrates cell cycle progression with DNA repair, replication, and G₂/M checkpoints

2002 • 1,102 citations

E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation

1996 • 765 citations

A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins

1997 • 750 citations

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1996 • 734 citations

Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1

1996 • 704 citations

Distinct roles for E2F proteins in cell growth control and apoptosis

1997 • 694 citations

The E2F1–3 transcription factors are essential for cellular proliferation

2001 • 595 citations

Apaf-1 is a transcriptional target for E2F and p53

2001 • 590 citations

BRCA1 Is Associated with a Human SWI/SNF-Related Complex

2000 • 548 citations

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1997 • 525 citations

Toward an understanding of the functional complexity of the E2F and retinoblastoma families.

1998 • 524 citations

In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts

1998 • 503 citations

Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation.

2001 • 436 citations

DNA Damage-Dependent Nuclear Dynamics of the Mre11 Complex

2001 • 392 citations

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase

1998 • 382 citations

BRCA1 interacts with components of the histone deacetylase complex

1999 • 330 citations

CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase

1999 • 328 citations

Negative Regulation of the Mammalian UV Response by Myc through Association with Miz-1

2002 • 306 citations

DNA replication control through interaction of E2F–RB and the origin recognition complex

2001 • 234 citations

BRCT Domain-containing Protein TopBP1 Functions in DNA Replication and Damage Response

2001 • 217 citations

Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

2001 • 214 citations

Binding of CtIP to the BRCT Repeats of BRCA1 Involved in the Transcription Regulation of p21 Is Disrupted Upon DNA Damage

1999 • 192 citations

E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2.

1998 • 190 citations

A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival

2002 • 187 citations

ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP

1999 • 181 citations

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

1997 • 132 citations

A DNA‐Topoisomerase‐11–Binding Protein with Eight Repeating Regions Similar to DNA‐repair Enzymes and to a Cell‐Cycle Regulator

1997 • 116 citations

Cooperation of HECT-domain Ubiquitin Ligase hHYD and DNA Topoisomerase II-binding Protein for DNA Damage Response

2002 • 104 citations

A Functional Interaction between the Human Papillomavirus 16 Transcription/Replication Factor E2 and the DNA Damage Response Protein TopBP1

2002 • 103 citations

Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA

1999 • 92 citations

The Drosophila mus101 Gene, Which Links DNA Repair, Replication and Condensation of Heterochromatin in Mitosis, Encodes a Protein With Seven BRCA1 C-Terminus Domains

2000 • 70 citations

Mutants suppressing in trans chorion gene amplification in Drosophila.

1984 • 63 citations

Cloning and characterization of the 5'-upstream sequence governing the cell cycle-dependent transcription of mouse DNA polymerase alpha 68 kDa subunit gene

2000 • 22 citations