MDMA (3,4-Methylenedioxymethamphetamine) or Ecstasy: The Neuropsychobiological Implications of Taking It at Dances and Raves

The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)

2003 • 1,251 citations

Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

1992 • 733 citations

Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings

1998 • 673 citations

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.

1987 • 526 citations

Understanding reasons for drug use amongst young people: a functional perspective

2001 • 441 citations

Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”)

1995 • 424 citations

Ecstasy (MDMA): a review of its possible persistent psychological effects

2000 • 386 citations

Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals

1985 • 371 citations

Ecstasy use in Australia: patterns of use and associated harm

1999 • 362 citations

Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research

2001 • 349 citations

Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat

1998 • 345 citations

Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

2002 • 323 citations

Behavioral Effects of Cannabinoid Agents in Animals

1999 • 311 citations

(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals

2000 • 296 citations

Drugs and the dance music scene: a survey of current drug use patterns among a sample of dance music enthusiasts in the UK

2001 • 274 citations

Psychobiological problems in heavy 'ecstasy' (MDMA) polydrug users

2000 • 267 citations

Cognitive performance and serotonergic function in users of ecstasy

2001 • 234 citations

Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies

2001 • 232 citations

Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat

1991 • 222 citations

Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems

2001 • 214 citations

(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Clinical Studies

2000 • 193 citations

An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine.

1998 • 183 citations

Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") polydrug users

2002 • 182 citations

3,4-Methylenedioxy analogues of amphetamine: Defining the risks to humans

1999 • 182 citations

Patterns of recreational drug use at dance events in Edinburgh, Scotland

2001 • 175 citations

Ecstasy use: cognitive deficits related to dosage rather than self-reported problematic use of the drug

2001 • 172 citations

Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users

2002 • 163 citations

Human Research on MDMA (3,4-Methylene- dioxymethamphetamine) Neurotoxicity: Cognitive and Behavioural Indices of Change

2000 • 157 citations

Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function

2004 • 154 citations

Causes and consequences of the loss of serotonergic presynapses elicited by the consumption of 3,4-methylenedioxymethamphetamine (MDMA, ?ecstasy?) and its congeners

1997 • 138 citations

Ecstasy (MDMA) in Recreational Users: Self-Reported Psychological and Physiological Effects

1997 • 137 citations

Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing

1995 • 130 citations

The Use of Drugs within the Techno Party Scene in European Metropolitan Cities

2001 • 129 citations

Differential effects of Ecstasy and cannabis on self‐reports of memory ability: a web‐based study

2001 • 129 citations

The action of some amines related to adrenaline. Cyclohexylalkylamines

1940 • 118 citations

Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice

2003 • 116 citations

Preliminary evidence of hippocampal dysfunction in adolescent MDMA (?ecstasy?) users: possible relationship to neurotoxic effects

2004 • 112 citations

Psychological Effects of MDE in Normal Subjects

1993 • 104 citations

Drug Use and Life Style Among College Undergraduates: A 30-Year Longitudinal Study

2001 • 102 citations

‘Weddings, parties, anything…’, a qualitative analysis of ecstasy use in Perth, Western Australia

2001 • 94 citations

Increased anxiety and "depressive" symptoms months after MDMA ("ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes

2003 • 93 citations

Cerebral1H MRS alterations in recreational 3,4-methylenedioxymethamphetamine (MDMA, ?ecstasy?) users

1999 • 89 citations

Potential Human Neurotoxicity of MDMA (‘Ecstasy’): Subjective Self-Reports, Evidence from an Italian Drug Addiction Centre and Clinical Case Studies

2000 • 84 citations

Patterns of Drug Use and the Influence of Gender on Self-Reports of Memory Ability in Ecstasy Users: A Web-Based Study

2003 • 83 citations

Heat increases 3,4-methylenedioxymethamphetamine self-administration and social effects in rats

2003 • 83 citations

Understanding drugs and behaviour

2005 • 69 citations

A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation

2001 • 66 citations

Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") but not by fenfluramine

1998 • 65 citations

The Love Drug: Marching to the Beat of Ecstasy

1998 • 62 citations

Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated (‘binge’ ingestion) low dose of MDMA

2004 • 57 citations

Reduced N-acetylaspartate levels in the frontal cortex of 3,4-methylenedioxymethamphetamine (Ecstasy) users: preliminary results.

2002 • 53 citations

Investigating the potential neurotoxicity of Ecstasy (MDMA): an imaging approach

2001 • 53 citations

Ecstasy/MDMA and cannabis: the complexities of their interactive neuropsychobiological effects

2004 • 41 citations

Methamphetamine toxicity in mice is potentiated by exposure to loud music

2001 • 38 citations

Emergency medical assistance during a mass gathering

1999 • 30 citations