Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated (‘binge’ ingestion) low dose of MDMA

The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)

2003 • 1,251 citations

Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

1992 • 733 citations

Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings

1998 • 673 citations

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

1988 • 548 citations

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.

1987 • 455 citations

Small Changes in Ambient Temperature Cause Large Changes in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Serotonin Neurotoxicity and Core Body Temperature in the Rat

1998 • 345 citations

Topical and Peripherally Acting Analgesics

2003 • 344 citations

Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

2002 • 323 citations

Neurotoxicity of MDMA and Related Compounds: Anatomic Studies^a

1990 • 251 citations

The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy')

1998 • 244 citations

The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats

2002 • 223 citations

Memory disturbances in ”Ecstasy" users are correlated with an altered brain serotonin neurotransmission

2000 • 215 citations

Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine.

1988 • 182 citations

Raves: a review of the culture, the drugs and the prevention of harm.

2000 • 175 citations

Multiple Severe Complications From Recreational Ingestion of MDMA ('Ecstasy')

1987 • 154 citations

Ecstasy, 3–4 Methylenedioxymethamphetamine (MDMA), a Fatality Associated with Coagulopathy and Hyperthermia

1991 • 143 citations

5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine

1993 • 137 citations

Hyperthermia following MDMA administration in rats: Effects of ambient temperature, water consumption, and chronic dosing

1995 • 130 citations

Toxicodynamics and long-term toxicity of the recreational drug, 3,4-methylenedioxymethamphetamine (MDMA, ‘Ecstasy’)

2000 • 124 citations

Adverse Reactions with 3,4-Methylenedioxymethamphetamine (MDMA; ???Ecstasy???)

1996 • 124 citations

Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice

2003 • 116 citations

Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or “ecstasy”) in rats

1994 • 111 citations

Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)

1988 • 110 citations

MDMA ("Ecstasy") and its association with cerebrovascular accidents: preliminary findings.

2000 • 103 citations

Factors influencing the toxicity of sympathomimetic amines to solitary mice.

1947 • 103 citations

Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats

1994 • 83 citations

Changes in Cardiovascular Responsiveness and Cardiotoxicity Elicited during Binge Administration of Ecstasy

2002 • 75 citations

A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation

2001 • 66 citations

Persistent loss of thermoregulation in the rat induced by 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") but not by fenfluramine

1998 • 65 citations

Methamphetamine toxicity in mice is potentiated by exposure to loud music

2001 • 38 citations

Involvement of serotonergic and dopaminergic mechanisms in hyperthermia induced by a serotonin-releasing drug, p-chloroamphetamine in mice

2001 • 28 citations