Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Numerical Recipes, The Art of Scientific Computing

1987 • 10,372 citations

Numerical recipes: the art of scientific computing

1987 • 3,090 citations

Advances in Drug Research

1964 • 615 citations

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity

1988 • 548 citations

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.

1987 • 526 citations

3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.

1987 • 455 citations

Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.

1987 • 451 citations

Correction for Scattered Radiation in a Ring Detector Positron Camera by Integral Transformation of the Projections

1983 • 398 citations

Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in Humans

1994 • 336 citations

Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

1996 • 312 citations

(±3,4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates

1988 • 294 citations

Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy")

1995 • 268 citations

Lasting effects of (+-)-3,4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.

1992 • 262 citations

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

1988 • 255 citations

Neurotoxicity of MDMA and Related Compounds: Anatomic Studies^a

1990 • 251 citations

Serotonin in Major Psychiatric Disorders

1990 • 177 citations

Positron emission tomography imaging of serotonin transporters in the human brain using [¹¹C](+)McN5652

1995 • 175 citations

3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.

1989 • 162 citations

In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain

1998 • 143 citations

Analysis of seasonal fluctuations of CSF monoamine metabolites and neuropeptides in normal controls: Findings with 5HIAA and HVA

1988 • 143 citations

Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)

1988 • 110 citations

Aminergic Metabolites in Cerebrospinal Fluid of Humans Previously Exposed to MDMA: Preliminary Observations^a

1990 • 106 citations

Extrapolation of Toxicological and Pharmacological Data from Animals to Humans

1991 • 104 citations

Analysis of [^C-11]Alpha-Methyl-Tryptophan Kinetics for the Estimation of Serotonin Synthesis RateIn Vivo

1997 • 104 citations

A PET radiotracer for studying serotonin uptake sites: carbon-11-McN-5652Z.

1993 • 103 citations

Kinetic Evaluation of [¹¹C]Dihydrotetrabenazine by Dynamic PET: Measurement of Vesicular Monoamine Transporter

1996 • 100 citations

5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates

1988 • 87 citations

Positron Emission Tomography of 5-HT Transporter Sites in the Baboon Brain with [¹¹C]McN5652

1995 • 72 citations

5-Hydroxytryptamine in Psychiatry

1991 • 63 citations

Studies of MDMA-Induced Neurotoxicity in Nonhuman Primates: A Basis for Evaluating Long-Term Effects in Humans

1989 • 46 citations

Synthesis of a radiotracer for studying serotonin uptake sites with positron emission tomography: [¹¹C]McN‐5652‐Z

1992 • 45 citations

Fenfluramine-induced loss of serotonin transporters in baboon brain visualized with PET

1996 • 13 citations