Export of proteins across membranes: The helix reversion hypothesis

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

1981 • 807 citations

Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein.

1981 • 644 citations

Amphiphilic Secondary Structure: Design of Peptide Hormones

1984 • 541 citations

Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

1977 • 529 citations

Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor.

1982 • 478 citations

Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein.

1981 • 414 citations

Trans‐membrane Translocation of Proteins

1979 • 364 citations

The ‘molten globule’ state is involved in the translocation of proteins across membranes?

1988 • 275 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

Conformations of Signal Peptides Induced by Lipids Suggest Initial Steps in Protein Export

1986 • 225 citations

Export of Protein: A Biochemical View

1987 • 184 citations

Nascent polypeptide chains emerge from the exit domain of the large ribosomal subunit: immune mapping of the nascent chain.

1982 • 142 citations

Structural and functional role of leucine residues in proteins

1973 • 135 citations

In Vivo Function and Membrane Binding Properties Are Correlated for Escherichia coli lamB Signal Peptides

1985 • 130 citations

Exploring the conformational roles of signal sequences: synthesis and conformational analysis of .lambda. receptor protein wild-type and mutant signal peptides

1984 • 117 citations

Selectivity of Intracellular Proteolysis: Protein Substrates Activate the ATP-Dependent Protease (La)

1986 • 112 citations

Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone.

1980 • 109 citations

On the translocation of proteins across membranes.

1987 • 95 citations

Translocation of nascent secretory proteins across membranes can occur late in translation.

1986 • 62 citations

Mathematical modeling of the effects of the signal recognition particle on translation and translocation of proteins across the endoplasmic reticulum membrane

1987 • 47 citations

Structure of the signal recognition particle by electron microscopy.

1985 • 45 citations

Post‐translational translocation of polypeptides across the mammalian endoplasmic reticulum membrane is size and ribosome dependent

1988 • 17 citations