The ‘molten globule’ state is involved in the translocation of proteins across membranes?

Protein Denaturation

1968 • 2,108 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Proteins as molecular chaperones

1987 • 910 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

Mechanisms of Intracellular Protein Breakdown

1982 • 647 citations

α‐lactalbumin: compact state with fluctuating tertiary structure?

1981 • 611 citations

Protein folding: Hypotheses and experiments

1987 • 544 citations

Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli

1986 • 473 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

How mitochondria import proteins

1984 • 405 citations

Native disulphide bond formation in protein biosynthesis: evidence for the role of protein disulphide isomerase

1984 • 293 citations

Comparison of the transient folding intermediates in lysozyme and .alpha.-lactalbumin

1985 • 281 citations

Compact state of a protein molecule with pronounced small-scale mobility: bovine ?-lactalbumin

1985 • 257 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

Sequential mechanism of refolding of carbonic anhydrase B

1987 • 199 citations

Protein unfolding and the energetics of protein translocation across biological membranes

1988 • 192 citations

Denaturation of Bovine Carbonic Anhydrase B by Guanidine Hydrochloride

1973 • 189 citations

Unfolding and refolding of a purified precursor protein during import into isolated mitochondria.

1988 • 182 citations

‘Molten‐globule“ state accumulates in carbonic anhydrase folding

1984 • 174 citations

Secretion of beta-lactamase into the periplasm of Escherichia coli: evidence for a distinct release step associated with a conformational change.

1986 • 133 citations

Point mutations destabilizing a precursor protein enhance its post-translational import into mitochondria.

1988 • 128 citations

Cell biology: An unfolding story of protein translocation

1986 • 126 citations

Latent membrane perturbation activity of a mitochondrial precursor protein is exposed by unfolding.

1988 • 120 citations

Import of an incompletely folded precursor protein into isolated mitochondria requires an energized inner membrane, but no added ATP.

1987 • 119 citations

On the translocation of proteins across membranes.

1987 • 95 citations

Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes.

1984 • 87 citations

Hydrophobic photolabeling identifies BHA2 as the subunit mediating the interaction of bromelain-solubilized influenza virus hemagglutinin with liposomes at low pH

1988 • 78 citations

Effects of sulphate and urea on the stability and reversible unfolding of β-lactamase from Staphylococcus aureus

1985 • 76 citations

Acid denaturation of bovine carbonic anhydrase B

1974 • 67 citations

Conformation of a stable intermediate on the folding pathway of Staphylococcus aureus penicillinase

1978 • 62 citations

Fusion of phospholipid vesicles induced by .alpha.-lactalbumin at acidic pH

1986 • 62 citations

Unfolding and refolding of Staphylococcus aureus penicillinase by urea-gradient electrophoresis

1980 • 61 citations

The pH-dependent conformational change of diphtheria toxin.

1988 • 58 citations

Conformation, stability, and folding of interleukin 1.beta.

1987 • 56 citations

Similarity of the conformation of diphtheria toxin at high temperature to that in the membrane-penetrating low-pH state.

1986 • 51 citations

The role of immunoglobulin heavy chain binding protein

1987 • 47 citations

[Acid form of carbonic anhydrase: "molten globule" with a secondary structure].

1983 • 31 citations

Protein translocation: A common mechanism for different membrane systems?

1986 • 31 citations

Regulation of the ubiquitin‐mediated proteolytic pathway: Role of the substrate α‐NH₂ group and of transfer RNA

1987 • 19 citations