Cloning and characterization of a human type II receptor for bone morphogenetic proteins.

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

1994 • 737 citations

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

1992 • 680 citations

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

1993 • 656 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

Characterization of Type I Receptors for Transforming Growth Factor-β and Activin

1994 • 558 citations

The TGF-β family and its composite receptors

1994 • 539 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

Bone and cartilage differentiation

1994 • 389 citations

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin.

1994 • 377 citations

Characterization and Cloning of a Receptor for BMP-2 and BMP-4 from NIH 3T3 Cells

1994 • 368 citations

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

1993 • 368 citations

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

1993 • 354 citations

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.

1988 • 354 citations

Bone Morphogenetic Proteins

1989 • 326 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1988 • 317 citations

A Transforming Growth Factor β Type I Receptor that Signals to Activate Gene Expression

1994 • 296 citations

A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the müllerian duct

1994 • 290 citations

Cloning, expression, and alternative splicing of the receptor for anti-Müllerian hormone.

1994 • 279 citations

Cloning of a Second Type of Activin Receptor and Functional Characterization in Xenopus Embryos

1992 • 226 citations

Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin.

1989 • 224 citations

Cloning of a Novel Type II Serine/Threonine Kinase Receptor through Interaction with the Type I Transforming Growth Factor-β Receptor

1995 • 189 citations

Recombinant human bone morphogenetic protein 2B stimulates PC12 cell differentiation: potentiation and binding to type IV collagen.

1992 • 162 citations

The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.

1994 • 145 citations

Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor.

1993 • 125 citations

Identification of a Drosophila activin receptor.

1993 • 114 citations

Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function.

1985 • 104 citations

Type I Receptors Specify Growth-Inhibitory and Transcriptional Responses to Transforming Growth Factor β and Activin

1994 • 70 citations

Signal transduction via serine/threonine kinase receptors

1994 • 50 citations

Osteogenic protein-1 regulates L1 and neural cell adhesion molecule gene expression in neural cells.

1993 • 48 citations