Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

Basic local alignment search tool

1990 • 87,358 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Transforming growth factor beta

2011 • 1,990 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Interleukin-6 and Its Receptor: A Paradigm for Cytokines

1992 • 889 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

1992 • 837 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Receptors for the TGF-β family

1992 • 638 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

Transcending the impenetrable: How proteins come to terms with membranes

1988 • 471 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

Purification and characterization of Erythroid Differentiation Factor(EDF) isolated from human leukemia cell line THP-1

1987 • 409 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

Transforming growth factors and the regulation of cell proliferation

1990 • 390 citations

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

1993 • 368 citations

Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta.

1989 • 346 citations

Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms

1990 • 342 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase

1990 • 293 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

TGF‐β Receptors and TGF‐β Binding Proteoglycans: Recent Progress in Identifying Their Functional Properties

1990 • 233 citations

Cloning of a Second Type of Activin Receptor and Functional Characterization in Xenopus Embryos

1992 • 226 citations

The Inhibin/Activin Family of Hormones and Growth Factors

1990 • 220 citations

The high molecular weight receptor to transforming growth factor-beta contains glycosaminoglycan chains.

1988 • 178 citations

Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk.

1992 • 156 citations

[17] Identification of receptor for type-β transforming growth factor

1987 • 134 citations

Identification of a Drosophila activin receptor.

1993 • 114 citations

Type beta transforming growth factor (TGF-β) is a potent stimulator of the basal secretion of follicle stimulating hormone (FSH) in a pituitary monolayer system

1986 • 107 citations

A surface component on GH3 pituitary cells that recognizes transforming growth factor-beta, activin, and inhibin.

1988 • 103 citations

Activin-A, Inhibin and Transforming Growth Factor-β Modulate Growth of Two Gonadal Cell Lines*

1989 • 100 citations

A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic factor

1993 • 91 citations

Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade.

1991 • 63 citations

Regulation of transformation-sensitive secreted phosphoprotein (SPPI/osteopontin) expression by transforming growth factor-β. Comparisons with expression of SPARC (secreted acidic cysteine-rich protein)

1991 • 50 citations

Multiple genes for Xenopus activin receptor expressed during early embryogenesis

1992 • 26 citations