NF-κB-Dependent Assembly of an Enhanceosome-Like Complex on the Promoter Region of Apoptosis Inhibitor Bfl-1/A1

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Signal transduction by tumor necrosis factor and its relatives

2001 • 1,623 citations

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB

2001 • 1,427 citations

Control of apoptosis by Rel/NF-κB transcription factors

1999 • 1,204 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome

1995 • 994 citations

CREB-binding protein/p300 are transcriptional coactivators of p65

1997 • 819 citations

Orchestrated response: a symphony of transcription factors for gene control

2000 • 763 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappa B that blocks TNFalpha -induced apoptosis

1999 • 721 citations

Ordered Recruitment of Chromatin Modifying and General Transcription Factors to the IFN-β Promoter

2000 • 716 citations

Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis

1998 • 643 citations

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1993 • 639 citations

The High Mobility Group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene

1992 • 632 citations

Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking

1997 • 610 citations

NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis

1999 • 574 citations

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

1995 • 546 citations

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

1993 • 530 citations

NF-κB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1999 • 526 citations

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

1998 • 433 citations

Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains

1995 • 422 citations

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

1999 • 410 citations

Distinct Mechanisms for Regulation of the Interleukin-8 Gene Involve Synergism and Cooperativity between C/EBP and NF-κB

1993 • 400 citations

Inhibition of TNF-induced apoptosis by NF-κB

1998 • 370 citations

Structure and Function of the Interferon- Enhanceosome

1998 • 354 citations

Enhanceosomes

2001 • 344 citations

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

1995 • 342 citations

Interaction and functional collaboration of p300 and C/EBPβ

1997 • 339 citations

Initiation of acute phase response and synthesis of cytokines

1996 • 338 citations

Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2.

1993 • 336 citations

The Mechanism of Transcriptional Synergy of an In Vitro Assembled Interferon-β Enhanceosome

1997 • 333 citations

The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance

2000 • 324 citations

Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways

2000 • 308 citations

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B.

1993 • 254 citations

Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter

1999 • 251 citations

Endothelial Cell Death Induced by Tumor Necrosis Factor-α Is Inhibited by the Bcl-2 Family Member, A1

1996 • 247 citations

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

2000 • 216 citations

Nucleosome Sliding via TBP DNA Binding In Vivo

2001 • 195 citations

Interleukin-1

1998 • 181 citations

Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells

1996 • 172 citations

The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome

1999 • 165 citations

A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow.

1995 • 147 citations

Different localization of the product of the v-rel oncogene in chicken fibroblasts and spleen cells correlates with transformation by REV-T

1986 • 142 citations

Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts.

1992 • 123 citations

Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun

1998 • 117 citations

Mechanism by which the IFN-β enhanceosome activates transcription

1999 • 112 citations

Mechanism of Rapid Transcriptional Induction of Tumor Necrosis Factor Alpha-Responsive Genes by NF-κB

2002 • 110 citations

Upregulation of Bcl-x and Bfl-1 as a potential mechanism of chemoresistance, which can be overcome by NF-κB inhibition

2000 • 109 citations

bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity.

1996 • 109 citations

c-Rel Arrests the Proliferation of HeLa Cells and Affects Critical Regulators of the G₁/S-Phase Transition

1997 • 106 citations

Regulation of HIV-1 Long Terminal Repeats by Interaction of C/EBP(NF-IL6) and NF-κB/Rel Transcription Factors

1996 • 104 citations

Functional Interaction of the v-Rel and c-Rel Oncoproteins with the TATA-Binding Protein and Association with Transcription Factor IIB

1993 • 102 citations

CCAAT/Enhancer-binding Protein Activates the CD14 Promoter and Mediates Transforming Growth Factor β Signaling in Monocyte Development

1999 • 81 citations

Activation of human monocytes induces differential resistance to apoptosis with rapid down regulation of caspase-8/FLICE

1998 • 80 citations

Long-Lived B Cells Are Distinguished by Elevated Expression of A1

1998 • 72 citations

Monocytes Stimulate Expression of the Bcl-2 Family Member, A1, in Endothelial Cells and Confer Protection Against Apoptosis

1999 • 72 citations

Downstream Activation of a TATA-less Promoter by Oct-2, Bob1, and NF-κB Directs Expression of the Homing Receptor BLR1 to Mature B Cells

1998 • 65 citations

NF- B mediated transcriptional activation is enhanced by the architectural factor HMGI-C

1998 • 58 citations

The IFN- Enhancer: A Paradigm for Understanding Activation and Repression of Inducible Gene Expression

1999 • 53 citations

Role of Nr13 in regulation of programmed cell death in the bursa of Fabricius

1999 • 50 citations

Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members

1999 • 50 citations

The CD40-Inducible Bcl-2 Family Member A1 Protects B Cells from Antigen Receptor-Mediated Apoptosis

2000 • 49 citations

Identification of a C/EBP-Rel Complex in Avian Lymphoid Cells

1994 • 45 citations

Rel blocks both anti-Fas- and TNFα-induced apoptosis and an intact Rel transactivation domain is essential for this effect

1998 • 44 citations

Cooperative binding and synergistic activation by RelA and C/EBPbeta on the intercellular adhesion molecule-1 promoter.

1998 • 37 citations

Expression of a novel Bcl-2 related gene, Bfl-1, in various human cancers and cancer cell lines.

1998 • 37 citations

GRS, a novel member of the Bcl-2 gene family, is highly expressed in multiple cancer cell lines and in normal leukocytes

1997 • 31 citations

Human A1, a Bcl-2-related gene, is induced in leukemic cells by cytokines as well as differentiating factors

1997 • 24 citations