Conserved Sr Protein Kinase Functions in Nuclear Import and Its Action Is Counteracted by Arginine Methylation inSaccharomyces cerevisiae

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

1994 • 2,554 citations

Conserved Structures and Diversity of Functions of RNA-Binding Proteins

1994 • 1,873 citations

hnRNP complexes: composition, structure, and function

1999 • 794 citations

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

1993 • 741 citations

The superfamily of arginine/serine-rich splicing factors.

1995 • 671 citations

SR proteins and splicing control.

1996 • 668 citations

Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors

1993 • 663 citations

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

1994 • 622 citations

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

1996 • 559 citations

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

1994 • 511 citations

Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity

1997 • 405 citations

Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

1997 • 394 citations

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

1994 • 325 citations

SRPK2: A Differentially Expressed SR Protein-specific Kinase Involved in Mediating the Interaction and Localization of Pre-mRNA Splicing Factors in Mammalian Cells

1998 • 306 citations

In Vivo and In Vitro Arginine Methylation of RNA-Binding Proteins

1995 • 302 citations

A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.

1996 • 298 citations

Arginine methylation facilitates the nuclear export of hnRNP proteins

1998 • 287 citations

Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

1995 • 282 citations

Interaction of U2AF ⁶⁵ RS Region with Pre-mRNA of Branch Point and Promotion Base Pairing with U2 snRNA

1996 • 279 citations

Specific commitment of different pre-mRNAs to splicing by single SR proteins

1993 • 272 citations

The SR protein family: pleiotropic functions in pre-mRNA splicing

1996 • 259 citations

Transportin-SR, a Nuclear Import Receptor for SR Proteins

1999 • 244 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

The Protein Kinase Clk/Sty Directly Modulates SR Protein Activity: Both Hyper- and Hypophosphorylation Inhibit Splicing

1999 • 223 citations

Nuclear export of proteins and RNAs

1997 • 209 citations

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors.

1994 • 199 citations

A Human Importin-β Family Protein, Transportin-SR2, Interacts with the Phosphorylated RS Domain of SR Proteins

2000 • 198 citations

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

1997 • 192 citations

The Predominant Protein-arginine Methyltransferase from Saccharomyces cerevisiae

1996 • 187 citations

Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p

1998 • 186 citations

Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA.

1977 • 177 citations

In Vivo Regulation of Alternative Pre-mRNA Splicing by the Clk1 Protein Kinase

1997 • 169 citations

SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome.

1995 • 167 citations

A Novel Methyltransferase (Hmt1p) Modifies Poly(A)⁺-RNA-Binding Proteins

1996 • 161 citations

Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants [published erratum appears in J Cell Biol 1994 Sep;126(6):1627]

1994 • 159 citations

Phosphorylation Regulates In Vivo Interaction and Molecular Targeting of Serine/Arginine-rich Pre-mRNA Splicing Factors

1999 • 146 citations

An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor.

1995 • 143 citations

hnRNP G: sequence and characterization of a glycosylated RNA-binding protein

1993 • 141 citations

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

1994 • 133 citations

Distribution of NG, NG-dimethylarginine in nuclear protein fractions

1977 • 125 citations

Conservation in budding yeast of a kinase specific for SR splicing factors

1999 • 125 citations

A Distinct and Parallel Pathway for the Nuclear Import of an mRNA-binding Protein

1997 • 104 citations

Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing

1993 • 104 citations

Analysis of the Yeast Arginine Methyltransferase Hmt1p/Rmt1p and Its in Vivo Function

2000 • 96 citations

Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps.

1995 • 86 citations

A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization.

1993 • 84 citations

The essential yeast RNA binding protein Npl3p is methylated

1996 • 84 citations

Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export

1999 • 77 citations

A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs

1991 • 77 citations

Phosphate groups modifying myelin basic proteins are metabolically labile; methyl groups are stable.

1983 • 76 citations

SF2 and SRp55 regulation of CD45 exon 4 skipping during T cell activation

1999 • 63 citations

Mammalian pre-mRNA splicing factors

1997 • 53 citations