Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Experimental pathology of the liver

1931 • 3,113 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Liver regeneration: molecular mechanisms of growth control

1990 • 922 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

1992 • 724 citations

Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.

1992 • 619 citations

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

1985 • 589 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Functional expression of cloned human splicing factor SF2: homology to rna-binding proteins, U1 70K, and drosophila splicing regulators

1991 • 508 citations

Identification of a Sequence in the PEPCK Gene That Mediates a Negative Effect of Insulin on Transcription

1990 • 369 citations

Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant.

1987 • 360 citations

Primary structure of the human splicing factor asf reveals similarities with drosophila regulators

1991 • 357 citations

Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon.

1975 • 329 citations

Regulation of Liver Growth: Protooncogenes and Transforming Growth Factors

1990 • 315 citations

A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.

1987 • 292 citations

Growth Factor-Induced Delayed Early Response Genes

1992 • 287 citations

Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro

1991 • 244 citations

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

1991 • 243 citations

Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts.

1989 • 236 citations

Role of Insulin in the Regulation of Protein Synthesis

1980 • 234 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

Insulin as a Potent, Specific Growth Factor in a Rat Hepatoma Cell Line

1981 • 221 citations

The immediate-early growth response in regenerating liver and insulin-stimulated H-35 cells: comparison with serum-stimulated 3T3 cells and identification of 41 novel immediate-early genes.

1991 • 216 citations

Induction patterns of 70 genes during nine days after hepatectomy define the temporal course of liver regeneration.

1993 • 205 citations

Interactions among LRF-1, JunB, c-Jun, and c-Fos define a regulatory program in the G1 phase of liver regeneration.

1992 • 188 citations

Proto-oncogene expression in regenerating liver is simulated in cultures of primary adult rat hepatocytes.

1986 • 167 citations

Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex.

1992 • 155 citations

Complexity of the primary genetic response to mitogenic activation of human T cells.

1989 • 149 citations

Immediate-early gene expression differs between regenerating liver, insulin-stimulated H-35 cells, and mitogen-stimulated Balb/c 3T3 cells. Liver-specific induction patterns of gene 33, phosphoenolpyruvate carboxykinase, and the jun, fos, and egr families.

1990 • 147 citations

Insulin as a growth factor in rat hepatoma cells. Stimulation of proto-oncogene expression.

1987 • 143 citations

Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing.

1992 • 131 citations

The gene encoding rat insulinlike growth factor-binding protein 1 is rapidly and highly induced in regenerating liver.

1991 • 110 citations

Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin.

1991 • 104 citations

Autoregulation and multifunctionality among trans-acting factors that regulate alternative pre-mRNA processing.

1992 • 80 citations

Insulin, glucagon, liver regeneration, and DNA synthesis

1976 • 78 citations

Characterization of the Promoter Region and 3′ End of the Human Insulin Receptor Gene

1989 • 74 citations

Induction of cyclin mRNA and cyclin-associated histone H1 kinase during liver regeneration.

1992 • 74 citations

Molecular cloning of gene sequences that are regulated by insulin-like growth factor I.

1987 • 71 citations

Stimulation of albumin gene transcription by insulin in primary cultures of rat hepatocytes

1987 • 50 citations

The role of the insulin receptor in mediating the insulin-stimulated growth response in Reuber H-35 cells

1984 • 34 citations

Molecular cloning of transcripts that accumulate during the late G1 phase in cultured mouse cells

1991 • 27 citations

Regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription

1991 • 26 citations

Liver regeneration in normal and alloxan‐induced diabetic rats

1977 • 24 citations