Parental Chromosome-specific Chromatin Conformation in the Imprinted U2af1-rs1 Gene in the Mouse

Role for DNA methylation in genomic imprinting

1994 • 1,695 citations

Effects of DNA methylation on DNA-binding proteins and gene expression

1993 • 732 citations

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1991 • 722 citations

Differential activity of maternally and paternally derived chromosome regions in mice

1985 • 708 citations

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1993 • 692 citations

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal

1993 • 602 citations

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

1989 • 554 citations

Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

1994 • 539 citations

Asynchronous Duplication of Chromosomes in Cultured Cells of Chinese Hamster

1960 • 530 citations

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.

1993 • 493 citations

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

1992 • 472 citations

Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

1994 • 430 citations

CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2

1990 • 426 citations

Parental-origin-specific epigenetic modification of the mouse H19 gene

1993 • 419 citations

A paternal–specific methylation imprint marks the alleles of the mouse H19 gene

1995 • 410 citations

Allele-specific replication timing of imprinted gene regions

1993 • 385 citations

Targeting Chromatin Disruption: Transcription Regulators that Acetylate Histones

1996 • 369 citations

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

1993 • 345 citations

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.

1992 • 279 citations

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes

1994 • 277 citations

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

1996 • 271 citations

Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene.

1987 • 241 citations

Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method

1994 • 219 citations

Parental imprinting of autosomal mammalian genes

1994 • 208 citations

The HNF-3 Gene Family of Transcription Factors in Mice: Gene Structure, cDNA Sequence, and mRNA Distribution

1994 • 204 citations

Specific protection of methylated CpGs in mammalian nuclei

1989 • 195 citations

A functional analysis of imprinting in parthenogenetic embryonic stem cells

1994 • 165 citations

Temporal and spatial regulation of H19 imprinting in normal and uniparental mouse embryos

1995 • 147 citations

Expression and methylation of imprinted genes during in vitro differentiation of mouse parthenogenetic and androgenetic embryonic stem cell lines

1994 • 145 citations

Unusual DNA structures, chromatin and transcription

1994 • 129 citations

Chromatin remodeling in mammalian zygotes

1992 • 128 citations

Inactive chromatin spreads from a focus of methylation.

1993 • 124 citations

A new imprinted gene cloned by a methylation-sensitive genome scanning method

1993 • 100 citations

Mouse U2af1-rs1 Is a Neomorphic Imprinted Gene

1997 • 99 citations

5-methylcytosine is localized in nucleosomes that contain histone H1.

1983 • 97 citations

Analysis of CpG methylation and genomic footprinting at the tyrosine aminotransferase gene: DNA methylation alone is not sufficient to prevent protein binding in vivo.

1991 • 95 citations

Genomic imprinting: causes and consequences.

1995 • 91 citations

Demethylation of specific sites in the 5' region of the inactive X-linked human phosphoglycerate kinase gene correlates with the appearance of nuclease sensitivity and gene expression.

1988 • 90 citations

Imprinted genes and regulation of gene expression by epigenetic inheritance

1996 • 88 citations

Dynamic methylation adjustment and counting as part of imprinting mechanisms.

1996 • 81 citations

A preference of histone H1 for methylated DNA.

1996 • 75 citations

Variation in epigenetic inheritance

1990 • 73 citations

Stage-Specific Induction and Regulation by Genomic Imprinting of the Mouse U2afbp-rs Gene during Preimplantation Development

1995 • 67 citations

Domain organization of allele–specific replication within the GABRB3 gene cluster requires a biparental 15q11–13 contribution

1995 • 61 citations

Comparative Analysis of Igf-2/H19 Imprinted Domain: Identification of a Highly Conserved Intergenic DNase I Hypersensitive Region

1994 • 54 citations

Allele-specific methylation and expression of an imprinted U2afl-rsl (SP2) gene

1995 • 53 citations

Binding of Histone H1 to DNA Is Indifferent to Methylation at CpG Sequences

1995 • 46 citations

Replication asynchrony between homologs 15q11.2: Cytogenetic evidence for genomic imprinting

1991 • 41 citations

Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid.

1992 • 35 citations

Chromatin structure and imprinting: Developmental control of DNase‐I sensitivity in the mouse insulin‐like growth factor 2 gene

1995 • 32 citations

Inactive Allele-Specific Methylation and Chromatin Structure of the Imprinted GeneU2af1-rs1on Mouse Chromosome 11

1996 • 30 citations

Maternal and paternal genomes function independently in mouse ova in establishing expression of the imprinted genes Snrpn and Igf2r: no evidence for allelic trans-sensing and counting mechanisms.

1996 • 16 citations