Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4+ T Cell Responses

HOW CELLS RESPOND TO INTERFERONS

1998 • 3,937 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

The lineage decisions of helper T cells

2002 • 1,678 citations

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

2004 • 1,657 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

Viruses and Interferons

2001 • 985 citations

Estimating the Precursor Frequency of Naive Antigen-specific CD8 T Cells

2002 • 584 citations

T Helper Cell Fate Specified by Kinase-Mediated Interaction of T-bet with GATA-3

2005 • 505 citations

Early Programming of T Cell Populations Responding to Bacterial Infection

2000 • 492 citations

Regulation of Antigen-Specific CD8 ⁺ T Cell Homeostasis by Perforin and Interferon-γ

2000 • 452 citations

Interferon γ Is Required for Activation-induced Death of T Lymphocytes

2002 • 423 citations

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1998 • 380 citations

Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR

2001 • 349 citations

Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells

2000 • 340 citations

CD4 Effector T Cell Subsets in the Response to Influenza

2002 • 328 citations

CD8+ T cell contraction is controlled by early inflammation

2004 • 322 citations

Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

2005 • 314 citations

Lack of Interferon γ Receptor β Chain and the Prevention of Interferon γ Signaling in T_H1 Cells

1995 • 292 citations

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

2004 • 180 citations

Epigenetic control in the immune response

2005 • 103 citations

Dynamic Regulation of IFN-γ Signaling in Antigen-Specific CD8+ T Cells Responding to Infection

2005 • 94 citations

A Distinct Region of the Murine IFN-γ Promoter Is Hypomethylated from Early T Cell Development through Mature Naive and Th1 Cell Differentiation, but Is Hypermethylated in Th2 Cells

2004 • 87 citations

Apoptotic Regulation of T Cells and Absence of Immune Deficiency in Virus-Infected Gamma Interferon Receptor Knockout Mice

1998 • 77 citations

The Rapidity with Which Virus-Specific CD8+ T Cells Initiate IFN-γ Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance

2004 • 57 citations

Characterization and use of monoclonal and polyclonal antibodies against the mouse interferon-γ receptor

1992 • 20 citations

Regulation of cell-surface receptors for human interferon-γ on the human histiocytic lymphoma cell line U937

1991 • 13 citations