Regulation of cell-surface receptors for human interferon-γ on the human histiocytic lymphoma cell line U937

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge

1988 • 428 citations

Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes.

1983 • 408 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

High specific activity iodination of gamma-globulin with iodine-131 monochloride.

1960 • 324 citations

Interferons as modulators of human monocyte-macrophage differentiation. I. Interferon-gamma increases HLA-DR expression and inhibits phagocytosis of zymosan.

1984 • 106 citations

Demonstration and partial characterization of the interferon-gamma receptor on human mononuclear phagocytes.

1985 • 97 citations

Continuous internalization of tumor necrosis factor receptors in a human myosarcoma cell line.

1988 • 97 citations

Suppression of murine collagen-induced arthritis with monoclonal anti-Ia antibodies and augmentation with IFN-gamma.

1988 • 92 citations

Internalization and degradation of receptor-bound interferon-gamma by murine macrophages. Demonstration of receptor recycling.

1987 • 82 citations

Purification and characterization of the human interferon-gamma receptor from placenta.

1988 • 80 citations

The characteristics of binding of human recombinant interferon-gamma to its receptor on human monocytes and human monocyte-like cell lines.

1985 • 80 citations

Receptor-mediated endocytosis of interleukin 2 in a human tumor T cell line. Degradation of interleukin 2 and evidence for the absence of recycling of interleukin receptors.

1986 • 64 citations

Binding and cross-linking of recombinant mouse interferon-gamma to receptors in mouse leukemic L1210 cells; interferon-gamma internalization and receptor down-regulation.

1986 • 55 citations

The recruitment of lymphocytes into the skin by T cell lymphokines: the role of gamma-interferon.

1988 • 51 citations

Direct evidence for an intracellular role for IFN-gamma. Microinjection of human IFN-gamma induces Ia expression on murine macrophages.

1990 • 48 citations

Macrophage activation for tumor cytotoxicity: regulatory mechanisms for induction and control of cytotoxic activity.

1982 • 48 citations

Identification of Gamma-Interferon as a Murine Macrophage-Activating Factor for Tumor Cytotoxicity

1984 • 40 citations

Two molecular forms of the human interferon-gamma receptor. Ligand binding, internalization, and down-regulation.

1988 • 33 citations

Internalization and degradation of human recombinant interferon-γ in the human histiocytic lymphoma cell line, U937: Relationship to Fc receptor enhancement and antiproliferation

1988 • 18 citations