The angiotensin‐converting enzyme (ACE) genetic polymorphism: its relationship with plasma ACE level and myocardial infarction

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

1990 • 3,809 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

1992 • 1,280 citations

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

1992 • 1,181 citations

Elevation of serum angiotension-converting-enzyme (ACE) level in sarcoidosis

1975 • 865 citations

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

1988 • 741 citations

Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes

1993 • 518 citations

Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension

1992 • 386 citations

[Angiotensin-I converting enzyme].

1995 • 335 citations

Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study.

1988 • 279 citations

Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension

1992 • 267 citations

Deletion polymorphism in angiotensin-converting enzyme gene associated with parental history of myocardial infarction

1993 • 262 citations

The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.

1992 • 253 citations

The angiotensin I converting enzyme gene and predisposition to high blood pressure.

1993 • 239 citations

Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes.

1991 • 197 citations

Distribution of plasma angiotensin I-converting enzyme levels in healthy men: relationship to environmental and hormonal parameters.

1991 • 185 citations

Angiotensin I‐converting Enzyme

1986 • 164 citations

Kinins mediate the antiproliferative effect of ramipril in rat carotid artery

1992 • 144 citations

Association Analysis of a Polymorphism of the Angiotensin Converting Enzyme Gene with Essential Hypertension in the Japanese Population

1993 • 134 citations

Mechanism of coronary vasodilation produced by bradykinin.

1991 • 86 citations

Role of Prostaglandins in the Cardiovascular Effects of Bradykinin and Angiotensin-Converting Enzyme Inhibitors

1992 • 75 citations

Increased angiotensin-converting enzyme in peripheral blood monocytes from patients with sarcoidosis.

1985 • 39 citations