Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

1990 • 3,809 citations

The world health organization monica project (monitoring trends and determinants in cardiovascular disease): A major international collaboration

1988 • 1,727 citations

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

1992 • 1,280 citations

Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels.

1992 • 1,181 citations

Essential Hypertension: Renin and Aldosterone, Heart Attack and Stroke

1972 • 1,098 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Coronary Vasospasm as a Possible Cause of Myocardial Infarction

1978 • 845 citations

Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.

1991 • 751 citations

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

1988 • 741 citations

Association of the Renin-Sodium Profile with the Risk of Myocardial Infarction in Patients with Hypertension

1991 • 734 citations

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

1989 • 558 citations

Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture.

1990 • 417 citations

Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension

1992 • 386 citations

Ramiprilat enhances endothelial autacoid formation by inhibiting breakdown of endothelium-derived bradykinin.

1991 • 361 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 288 citations

Familial resemblance of plasma angiotensin-converting enzyme level: the Nancy Study.

1988 • 279 citations

A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study.

1992 • 238 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 230 citations

Distribution of plasma angiotensin I-converting enzyme levels in healthy men: relationship to environmental and hormonal parameters.

1991 • 185 citations

Kinins mediate the antiproliferative effect of ramipril in rat carotid artery

1992 • 144 citations

Mechanism of coronary vasodilation produced by bradykinin.

1991 • 86 citations

Unique cardioprotective potential of angiotensin converting enzyme inhibitors: a hypothesis still to be tested on humans

1991 • 8 citations