Chronic antidepressant treatment and central 5-HT synapses

Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system

1978 • 809 citations

Two Distinct Central Serotonin Receptors with Different Physiological Functions

1981 • 640 citations

Tricyclic Antidepressants: Long-Term Treatment Increases Responsivity of Rat Forebrain Neurons to Serotonin

1978 • 476 citations

Characteristics of central 5-HT receptors and their adaptive changes following intracerebral 5,7-dihydroxytryptamine administration in the rat.

1978 • 336 citations

Specific tricyclic antidepressant binding sites in rat brain

1979 • 266 citations

Specific tricyclic antidepressant binding sites in rat brain characterised by high-affinity 3H-imipramine binding

1980 • 249 citations

The effects of monoamine neurotoxins on peptides in the rat spinal cord

1982 • 234 citations

Regulation of serotonin2 (5-HT2) receptors labeled with [3H]spiroperidol by chronic treatment with the antidepressant amitriptyline.

1980 • 207 citations

Reevaluation of the indoleamine hypothesis of depression. Evidence for a reduction of functional activity of central 5-HT systems by antidepressant drugs

1979 • 181 citations

High-affinity binding of 3H-imipramine in brain and platelets and its relevance to the biochemistry of affective disorders

1981 • 145 citations

Adenosine Receptors Mediating Cyclic AMP Productioin the Rat Hippocampus

1982 • 137 citations

High-affinity 3H-imipramine binding in rat cerebral cortex

1979 • 127 citations

Aspects on receptor regulation and isoreceptor identification.

1980 • 126 citations

Typical and atypical antidepressants

1983 • 126 citations

High-affinity [3H]desipramine binding in the peripheral and central nervous system: A specific site associated with the neuronal uptake of noradrenaline

1982 • 120 citations

Chronic antidepressant treatment enhances α-adrenergic and serotonergic responses in the facial nucleus

1980 • 120 citations

The pharmacology of zimelidine: A 5‐HT selective reuptake inhibitor

1981 • 110 citations

Down regulation of dihydroalprenolol and imipramine binding sites in brain of rats repeatedly treated with imipramine

1980 • 95 citations

High-affinity 3H-imipramine binding: a new biological tool for studies in depression

1981 • 82 citations

Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia

1980 • 74 citations

Pre‐ and postsynaptic effects of zimelidine and norzimelidine on the serotoninergic system: single cell studies in the rat

1981 • 72 citations

Serotonin and the regulation of pituitary hormone secretion and of neuroendocrine rhythms.

1981 • 58 citations

Depolarization-evoked accumulation of cyclic AMP in brain slices: inhibition by exogenous adenosine deaminase

1973 • 53 citations

Role of the Raphe Nuclei in Stimulation Producing Analgesia

1981 • 51 citations

Adenosine and Cyclic AMP in Rat Cerebral Cortical Slices: Effects of Adenosine Uptake Inhibitors and Adenosine Deaminase Inhibitors

1981 • 49 citations

The effects of chronic treatment with the 5-hydroxytryptamine uptake blocker zimelidine on central 5-hydroxytryptamine mechanisms. Evidence for the induction of a low affinity binding site for 5-hydroxytryptamine

1979 • 47 citations

Serotoninergic receptors in brain tissue: properties and identification of various 3H-ligand binding sites in vitro.

1981 • 39 citations

Long-term treatment with zimelidine leads to a reduction in 5-hydroxytryptamine neurotransmission within the central nervous system of the mouse and rat

1981 • 38 citations

Descending Control of Pain Transmission: Possible Serotonergic-Enkephalinergic Interactions

1981 • 37 citations

Role of Serotonin in the Hypothalamic Regulation of Pituitary Function

1981 • 25 citations

Regional differences in neuronal responses to 5-HT: intracellular studies in hippocampal slices.

1981 • 22 citations

Serotonin-Receptors Coupled with an Adenylate Cyclase in the Rat Brain: Non-Identity with 3H-5-HT Binding Sites

1981 • 19 citations

The Action of Serotonin in the Rat Hippocampus

1981 • 12 citations

The effects of subchronic antidepressant drug treatment on the secretion of adenohypophyseal hormones and of corticosterone in the male rat.

1982 • 7 citations