PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells

Dendritic cells and the control of immunity

1998 • 14,345 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

1996 • 1,115 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family

1995 • 810 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

Selective Defects in the Development of the Fetal and Adult Lymphoid System in Mice with an Ikaros Null Mutation

1996 • 619 citations

Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes.

1997 • 524 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

Ikaros, an Early Lymphoid-Specific Transcription Factor and a Putative Mediator for T Cell Commitment

1992 • 458 citations

RelB Is Essential for the Development of Myeloid-Related CD8α− Dendritic Cells but Not of Lymphoid-Related CD8α+ Dendritic Cells

1998 • 443 citations

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny.

1996 • 405 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Dendritic cells: from ontogenetic orphans to myelomonocytic descendants

1996 • 324 citations

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.

1993 • 315 citations

PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors

1998 • 296 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

PU.1 Functions in a Cell-Autonomous Manner to Control the Differentiation of Multipotential Lymphoid–Myeloid Progenitors

1997 • 276 citations

A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.

1996 • 238 citations

Transcription Factors and Hematopoietic Development

1995 • 236 citations

Cell-Autonomous Defects in Dendritic Cell Populations of Ikaros Mutant Mice Point to a Developmental Relationship with the Lymphoid Lineage

1997 • 221 citations

Dendritic Cell Development: Multiple Pathways to Nature's Adjuvants

1997 • 217 citations

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

1993 • 211 citations

PU.1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation

1995 • 200 citations

Role of PU.1 in Hematopoiesis

1998 • 159 citations

Expression of relB transcripts during lymphoid organ development: specific expression in dendritic antigen-presenting cells

1993 • 149 citations

Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation

1995 • 138 citations

The linkage between T‐cell and dendritic cell development in the mouse thymus

1998 • 118 citations

Dendritic Cell Development and Maturation

1997 • 109 citations

T Cell Development in PU.1-Deficient Mice

1999 • 102 citations