Desensitization of Platelet-Derived Growth Factor Receptor-β by Oxidized Lipids in Vascular Cells and Atherosclerotic Lesions

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Beyond Cholesterol

1989 • 6,533 citations

Atherosclerosis

2000 • 4,558 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

2003 • 1,119 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

The oxidative modification hypothesis of atherogenesis: an overview

2000 • 749 citations

The thin-cap fibroatheroma: a type of vulnerable plaque: The major precursor lesion to acute coronary syndromes

2001 • 673 citations

Protein-bound acrolein: Potential markers for oxidative stress

1998 • 622 citations

Platelet-derived growth factor receptor signals.

1994 • 561 citations

Biochemical structural and functional properties of oxidized low-density lipoprotein

1990 • 536 citations

Mechanisms of plaque vulnerability and rupture

2003 • 520 citations

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

1990 • 478 citations

Distinct monoubiquitin signals in receptor endocytosis

2003 • 436 citations

Vascular Smooth Muscle Growth: Autocrine Growth Mechanisms

2001 • 383 citations

Oxidized Low Density Lipoprotein Displaces Endothelial Nitric-oxide Synthase (eNOS) from Plasmalemmal Caveolae and Impairs eNOS Activation

1999 • 357 citations

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes.

1993 • 334 citations

Oxidized low-density lipoprotein-induced apoptosis

2002 • 323 citations

Hydralazine prevents nitroglycerin tolerance by inhibiting activation of a membrane-bound NADH oxidase. A new action for an old drug.

1996 • 312 citations

Evidence for Distinct Signaling Properties and Biological Responses Induced by the PDGF Receptor α and β Subtypes

1999 • 197 citations

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.

1991 • 166 citations

Functional Blockade of Platelet-Derived Growth Factor Receptor-β but Not of Receptor-α Prevents Vascular Smooth Muscle Cell Accumulation in Fibrous Cap Lesions in Apolipoprotein E–Deficient Mice

2001 • 166 citations

Oxidized Phospholipids Trigger Atherogenic Inflammation in Murine Arteries

2005 • 142 citations

Neurotrophin receptor p75NTR characterizes human esophageal keratinocyte stem cells in vitro

2003 • 141 citations

Activation of EGF receptor by oxidized LDL

1998 • 141 citations

Current Concepts in Cardiovascular Pathology: The Role of LDL Cholesterol in Plaque Rupture and Stabilization

1998 • 137 citations

Oxidized LDLs alter the activity of the ubiquitin‐proteasome pathway: potential role in oxidized LDL‐induced apoptosis

2000 • 121 citations

Oxidized LDL-Induced Smooth Muscle Cell Proliferation Involves the EGF Receptor/PI-3 Kinase/Akt and the Sphingolipid Signaling Pathways

2002 • 120 citations

Two Distinct Calcium-Dependent Mitochondrial Pathways Are Involved in Oxidized LDL-Induced Apoptosis

2004 • 114 citations

HDL counterbalance the proinflammatory effect of oxidized LDL by inhibiting intracellular reactive oxygen species rise, proteasome activation, and subsequent NF‐κB activation in smooth muscle cells

2003 • 102 citations

Oxidation of LDL, Atherogenesis, and Apoptosis

2003 • 96 citations

Regulation of cell growth by oxidized LDL

2000 • 93 citations

Expression of platelet-derived growth factor B-chain in neointimal smooth muscle cells of balloon injured rabbit femoral arteries

1996 • 91 citations

NAD(P)H Oxidases and Their Relevance to Atherosclerosis

2001 • 91 citations

Interaction of native and modified low-density lipoproteins with extracellular matrix

2000 • 83 citations

Reversible inhibition of DNA and protein synthesis by cumene hydroperoxide and 4-hydroxy-nonenal

1988 • 62 citations

Mildly Oxidized LDL Induces Activation of Platelet-Derived Growth Factor β-Receptor Pathway

2001 • 61 citations

The Consequences of Lipid Peroxidation in Isolated Hepatocytes

1975 • 61 citations

Platelet Derived Growth Factor-BB is a Potent Mitogen for Rat Ureteral and Human Bladder Smooth Muscle Cells: Dependence in Lipid Rafts for Cell Signaling

2003 • 57 citations

Deleted Work

1955 • 0 citations