Apoptosis: A Functional Paradigm for Programmed Plant Cell Death Induced by a Host-Selective Phytotoxin and Invoked during Development.

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response

1994 • 2,757 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

1995 • 1,171 citations

Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme

1991 • 1,094 citations

Apoptosis: The Biochemistry and Molecular Biology of Programmed Cell Death*

1993 • 1,005 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Molecular regulation of apoptosis: Genetic controls on cell death

1993 • 923 citations

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1995 • 835 citations

An evolutionary perspective on apoptosis

1994 • 758 citations

Gene expression during leaf senescence

1994 • 720 citations

Arabidopsis mutants simulating disease resistance response

1994 • 718 citations

GENE-FOR-GENE COMPLEMENTARITY IN PLANT-PATHOGEN INTERACTIONS

1990 • 715 citations

Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

1994 • 697 citations

Apoptosis and disease

1993 • 684 citations

Programmed cell death in plants: A pathogen-triggered response activated coordinately with multiple defense functions

1994 • 670 citations

Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).

1993 • 554 citations

Apoptosis: a different type of cell death

1992 • 523 citations

Fumonisins, Mycotoxins Produced by Fusarium Species: Biology, Chemistry, and Significance

1993 • 475 citations

Chapter 1 Anatomical Methods in Cell Death

1995 • 475 citations

Natural occurrence of some Fusarium mycotoxins in corn from low and high esophageal cancer prevalence areas of the Transkei, Southern Africa

1990 • 462 citations

Internucleosomal DNA Cleavage Should not be the Sole Criterion for Identifying Apoptosis

1992 • 462 citations

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

1994 • 459 citations

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats

1990 • 457 citations

Cleavage of Nuclear DNA into Oligonucleosomal Fragments during Cell Death Induced by Fungal Infection or by Abiotic Treatments.

1996 • 387 citations

A rapid and inexpensive method for isolation of total DNA from dehydrated plant tissue

1990 • 330 citations

Fumonisin contamination of commercial corn-based human foodstuffs

1991 • 305 citations

Production of fumonisins by Fusarium moniliforme and Fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary edema syndrome in swine

1990 • 304 citations

The implications of naturally occurring levels of fumonisins in corn for human and animal health

1992 • 292 citations

The genetic regulation of apoptosis

1995 • 283 citations

Eicosapentaenoic and Arachidonic Acids from Phytophthora infestans Elicit Fungitoxic Sesquiterpenes in the Potato

1981 • 270 citations

Fumonisin- and AAL-Toxin-Induced Disruption of Sphingolipid Metabolism with Accumulation of Free Sphingoid Bases

1994 • 267 citations

Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging

1993 • 266 citations

Apoptosis: Molecular Control Point in Toxicity

1994 • 263 citations

Sphingosine 1-phosphate generated in the endoplasmic reticulum membrane activates release of stored calcium.

1994 • 253 citations

Ceramide: A stress signal and mediator of growth suppression and apoptosis

1995 • 233 citations

Apoptosis and Its Role in Human Disease

1994 • 232 citations

Expression of Ethylene Biosynthetic Pathway Transcripts in Senescing Carnation Flowers

1992 • 232 citations

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

1995 • 228 citations

Interorgan regulation of ethylene biosynthetic genes by pollination.

1993 • 224 citations

Ovary and Gametophyte Development Are Coordinately Regulated by Auxin and Ethylene following Pollination.

1993 • 212 citations

Coordinated Activation of Programmed Cell Death and Defense Mechanisms in Transgenic Tobacco Plants Expressing a Bacterial Proton Pump.

1995 • 206 citations

Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

1994 • 202 citations

Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation.

1995 • 197 citations

Plant disease resistance genes in signal perception and transduction

1994 • 184 citations

Endonuclease activation during apoptosis: The role of cytosolic Ca2+ and pH

1992 • 179 citations

Single‐step procedure for labeling DNA strand breaks with fluorescein‐ or Bodipy‐conjugated deoxynucleotides: Detection of apoptosis and bromodeoxyuridine incorporation

1995 • 178 citations

Active Oxygen Production During a Bacteria-Induced Hypersensitive Reaction in Tobacco Suspension Cells

1989 • 175 citations

Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.

1994 • 169 citations

Fumonisins and other inhibitors of de novo sphingolipid biosynthesis.

1993 • 163 citations

Production and Nature of a Host-Specific Toxin from Alternaria alternata f. sp. lycopersici

1976 • 162 citations

Fumonisins‐mycotoxins produced byfusarium moniliforme

1993 • 151 citations

Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme.

1994 • 147 citations

Evidence That Ceramide Selectively Inhibits Protein Kinase C-α Translocation and Modulates Bradykinin Activation of Phospholipase D

1995 • 139 citations

The cancer-initiating potential of the fumonisin B mycotoxins

1992 • 138 citations

Apoptosis: Suicide,execution or murder?

1993 • 138 citations

Totipotency of tomato protoplasts

1985 • 136 citations

Apoptosis: a gene-directed programme of cell death.

1992 • 115 citations

Detection of fumonisins B1, B2, and B3 and hydrolyzed fumonisin B1 in corn-containing foods

1993 • 115 citations

Apoptosis: Final control point in cell biology

1992 • 112 citations

Microcinematographic and electron microscopic analysis of target cell lysis induced by cytotoxic T lymphocytes.

1979 • 111 citations

A Stem Canker Disease of Tomato Caused by Alternaria alternata f. sp. lycopersici

1975 • 111 citations

Phytotoxins. II. Characterization of a phytotoxic fraction from alternaria alternata f. sp. lycopersici

1981 • 109 citations

Perturbation of the ubiquitin system causes leaf curling, vascular tissue alterations and necrotic lesions in a higher plant.

1990 • 108 citations

In vitro toxicology of fumonisins and the mechanistic implications

1992 • 106 citations

The ins and outs of programmed cell death duringC. elegansdevelopment

1994 • 100 citations

Cadmium- and Zinc-Mediated Changes of the Ca2+-Dependent Endonuclease in Apoptosis

1993 • 99 citations

Suppression of apoptosis in insect cells stably transfected with baculovirus p35: dominant interference by N-terminal sequences p35(1-76)

1994 • 97 citations

Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate.

1994 • 76 citations

Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases.

1995 • 64 citations

Interaction of theascLocus in F₈Paired Lines of Tomato withAlternaria alternataf. sp.lycopersiciand AAL-Toxin

1987 • 64 citations

Genetic and physiological response to fumonisin and AAL-toxin by intact tissue of a higher plant

1992 • 57 citations

Sphingosine-related mycotoxins in plant and animal diseases

1995 • 56 citations

Properties of host specific toxins produced by Alternaria alternata f. sp. lycopersici in culture and in tomato plants

1983 • 53 citations

Ceramide: A Potential Second Messenger in the Nervous System

1995 • 49 citations

Structural characterization of three new AAL toxins produced by Alternaria alternata f. sp. lycopersici

1994 • 47 citations

Evolutionary Conservation of Function Among Mammalian, Avian, and Viral Homologs of the Bcl-2 Oncoprotein

1994 • 43 citations

Antigen-Induced Programmed T Cell Death as a New Approach to Immune Therapy

1995 • 39 citations

AAL-toxin induced physiological changes in Lycopersicon esculentum Mill: roles for ethylene and pyrimidine intermediates in necrosis

1994 • 34 citations

Tracing Tracheary Element Development

1994 • 29 citations

Electrospray Ionization Mass Spectrometry of Sphinganine Analog Mycotoxins

1995 • 28 citations

STRUCTURE AND DYNAMICS OF THE ROOT CAP OF AVENA SATIVA L.*

1973 • 23 citations

Chemistry and Biological Activity of AAL Toxins

1996 • 23 citations

Behaviour of the disease resistance gene Asc in protoplasts of Lycopersicon esculentum mill

1993 • 16 citations

The Molecular Biology of Pectic Enzyme Production and Bacterial Soft Rot Pathogenesis

1986 • 7 citations

Potential applications of apoptosis in modifying the biological behavior of therapeutically refractory cancers

1994 • 3 citations