Region‐specific expression of immunoregulatory proteins on microglia in the healthy CNS

Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

2005 • 5,087 citations

ATP mediates rapid microglial response to local brain injury in vivo

2005 • 3,543 citations

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

2007 • 3,382 citations

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1990 • 1,897 citations

Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

2006 • 1,540 citations

Control of microglial neurotoxicity by the fractalkine receptor

2006 • 1,422 citations

Immune function of microglia

2001 • 1,245 citations

Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

2000 • 983 citations

Selective Ablation of Proliferating Microglial Cells Exacerbates Ischemic Injury in the Brain

2007 • 838 citations

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis

2005 • 831 citations

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

2007 • 829 citations

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

2007 • 804 citations

Neuronal ‘On’ and ‘Off’ signals control microglia

2007 • 736 citations

Experimental autoimmune encephalomyelitis repressed by microglial paralysis

2005 • 711 citations

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis

2005 • 666 citations

Promotion of Tissue Inflammation by the Immune Receptor Tim-3 Expressed on Innate Immune Cells

2007 • 657 citations

Microglia in health and disease

2005 • 651 citations

Neurotransmitter receptors on microglia

2007 • 602 citations

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

2001 • 427 citations

Microglial phenotype: is the commitment reversible?

2006 • 421 citations

Brain Dendritic Cells and Macrophages/Microglia in Central Nervous System Inflammation

2001 • 410 citations

Microglial senescence: does the brain's immune system have an expiration date?

2006 • 380 citations

Mature microglia resemble immature antigen-presenting cells

1998 • 339 citations

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

1995 • 326 citations

Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia

2002 • 316 citations

Control of glial immune function by neurons

2001 • 315 citations

Regional Effects of Wheel Running and Environmental Enrichment on Cell Genesis and Microglia Proliferation in the Adult Murine Neocortex

2003 • 308 citations

Microglia:Neuroprotective and Neurotrophic Cells in the Central Nervous System

2004 • 253 citations

CXCR3-Dependent Microglial Recruitment Is Essential for Dendrite Loss after Brain Lesion

2004 • 248 citations

Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis

2007 • 244 citations

Transient neuroprotection by minocycline following traumatic brain injury is associated with attenuated microglial activation but no changes in cell apoptosis or neutrophil infiltration

2006 • 237 citations

Microglial Expression of MHC Class II Increases in Normal Aging of Nonhuman Primates

1998 • 228 citations

Microglia

2004 • 216 citations

The Clinical Course of Experimental Autoimmune Encephalomyelitis and Inflammation Is Controlled by the Expression of Cd40 within the Central Nervous System

2001 • 215 citations

Dopamine and noradrenaline control distinct functions in rodent microglial cells

2005 • 214 citations

Neuronal expression of CD22: Novel mechanism for inhibiting microglial proinflammatory cytokine production

2004 • 164 citations

Functional Maturation of Adult Mouse Resting Microglia into an APC Is Promoted by Granulocyte-Macrophage Colony-Stimulating Factor and Interaction with Th1 Cells

2000 • 152 citations

Tumor Necrosis Factor α But Not Interleukin 1β Mediates Neuroprotection in Response to Acute Nitric Oxide Excitotoxicity

2006 • 131 citations

CD45 Opposes β-Amyloid Peptide-Induced Microglial Activation via Inhibition of p44/42 Mitogen-Activated Protein Kinase

2000 • 128 citations

Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis

2003 • 123 citations

Differential activation of microglia in neurogenic versus non‐neurogenic regions of the forebrain

2006 • 101 citations

CNS dendritic cells: Critical participants in CNS inflammation?

2006 • 92 citations

Optimized isolation enables ex vivo analysis of microglia from various central nervous system regions

2007 • 81 citations

Mouse resident microglia: Isolation and characterization of immunoregulatory properties with naïve CD4⁺and CD8⁺T‐cells

1998 • 78 citations

Parenchymal Microglia of Naı̈ve Adult C57BL/6J Mice Express High Levels of B7.1, B7.2, and MHC Class II

2002 • 64 citations

Mouse resident microglia: Isolation and characterization of immunoregulatory properties with na�ve CD4+ and CD8+ T-cells

1998 • 60 citations

Constitutive expression of a costimulatory ligand on antigen‐presenting cells in the nervous system drives demyelinating disease

2003 • 54 citations

Enriched immune-environment of blood–brain barrier deficient areas of normal adult rats

1997 • 43 citations

Site-specific immune regulation in the brain: Differential modulation of major histocompatibility complex (MHC) proteins in brainstem vs. hippocampus

1999 • 43 citations

Heterogeneity of antigen expression and lectin labeling on microglial cells in the olfactory bulb of adult rats

1997 • 26 citations