ATP mediates rapid microglial response to local brain injury in vivo

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

Analysis of Fractalkine Receptor CX₃CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

2000 • 2,356 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Long-term dendritic spine stability in the adult cortex

2002 • 1,186 citations

MICROGLIA AS MEDIATORS OF INFLAMMATORY AND DEGENERATIVE DISEASES

1999 • 977 citations

New Insights into Neuron-Glia Communication

2002 • 918 citations

Intercellular Calcium Signaling in Astrocytes via ATP Release through Connexin Hemichannels

2002 • 836 citations

ATP Released from Astrocytes Mediates Glial Calcium Waves

1999 • 794 citations

Connexins regulate calcium signaling by controlling ATP release

1998 • 767 citations

Dynamics of microglial activation: A confocal time-lapse analysis in hippocampal slices

2001 • 563 citations

Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through G_i/o-Coupled P2Y Receptors

2001 • 549 citations

Storage and Release of ATP from Astrocytes in Culture

2003 • 489 citations

P2X7 receptor inhibition improves recovery after spinal cord injury

2004 • 480 citations

Basic principles of immunological surveillance of the normal central nervous system

2001 • 480 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

ATP-Mediated Glia Signaling

2000 • 391 citations

Gap junctions and connexin expression in the normal and pathological central nervous system

2002 • 329 citations

Microglial activation by purines and pyrimidines

2002 • 310 citations

Glial neuronal signaling in the central nervous system

2003 • 306 citations

ATP‐induced ATP release from astrocytes

2003 • 237 citations

Astrocyte Ca²⁺waves trigger responses in microglial cells in brain slices

2001 • 236 citations

Involvement of astrocytes in purine‐mediated reparative processes in the brain

2001 • 234 citations

ATP Mediates Calcium Signaling Between Astrocytes and Microglial Cells: Modulation by IFN-γ

2001 • 232 citations

Direct Observation of Calcium-Independent Intercellular ATP Signaling in Astrocytes

2000 • 216 citations

Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton

1996 • 197 citations

Evidence that the gap junction protein connexin-43 is the ATP-induced pore of mouse macrophages

1991 • 195 citations

In VivoMeasurement of Brain Extracellular Space Diffusion by Cortical Surface Photobleaching

2004 • 195 citations

GLIAL CELLS IN NEUROTOXICITY DEVELOPMENT

1999 • 190 citations

Molecular physiology of P2 receptors in the central nervous system

2003 • 164 citations

Photoliberating inositol-1,4,5-trisphosphate triggers ATP release that is blocked by the connexin mimetic peptide gap 26

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Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices

2004 • 140 citations

Extracellular metabolism of nucleotides in the nervous system

1996 • 97 citations

Closure of Gap Junction Channels by Arylaminobenzoates

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Phagocytozing ameboid microglial cells studied in a mouse corpus callosum slice preparation

1996 • 92 citations

Rapid and Widespread Microglial Activation Induced by Traumatic Brain Injury in Rat Brain Slices

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Function of microglia in organotypic slice cultures

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Microglial phagocytosis is modulated by pro-and anti-inflammatory cytokines

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Haloperidol Prevents Ketamine- and Phencyclidine-Induced HSP70 Protein Expression but Not Microglial Activation

1996 • 56 citations

Controlled Damage in Thick Specimens by Multiphoton Excitation

2003 • 54 citations