REGIONALIZATION OF THE PROSENCEPHALIC NEURAL PLATE

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

1995 • 1,175 citations

Patterning the Vertebrate Neuraxis

1996 • 1,151 citations

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

1996 • 1,140 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

1993 • 1,086 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

1995 • 886 citations

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord

1994 • 869 citations

Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity

1996 • 866 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization

1993 • 777 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

Midbrain development induced by FGF8 in the chick embryo

1996 • 734 citations

Diversity and Pattern in the Developing Spinal Cord

1996 • 714 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

Origin and organization of the zebrafish fate map

1990 • 692 citations

Mouse Otx2 functions in the formation and patterning of rostral head.

1995 • 690 citations

Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation

1995 • 683 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

The role ofPax-6in eye and nasal development

1995 • 660 citations

Inductive interactions direct early regionalization of the mouse forebrain

1997 • 651 citations

Longitudinal organization of the anterior neural plate and neural tube

1995 • 647 citations

The Avian Embryo: Structural and Functional Development

1961 • 614 citations

Pax2 contributes to inner ear patterning and optic nerve trajectory

1996 • 588 citations

Roles of Pax-genes in developing and adult brain as suggested by expression patterns

1994 • 582 citations

Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt- 3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries

1993 • 570 citations

Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres

1995 • 569 citations

Patterning activities of vertebrate hedgehog proteins in the developing eye and brain

1995 • 557 citations

Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube

1995 • 542 citations

Mutations of the Homeobox Genes Dlx-1 and Dlx-2 Disrupt the Striatal Subventricular Zone and Differentiation of Late Born Striatal Neurons

1997 • 535 citations

The Embryonic Vertebrate Forebrain: the Prosomeric Model

1994 • 530 citations

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain

1996 • 502 citations

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

1995 • 491 citations

Induction of midbrain dopaminergic neurons by Sonic hedgehog

1995 • 481 citations

Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development

1996 • 440 citations

The Xenopus homologue of Otx2 is a maternal homeobox gene that demarcates and specifies anterior body regions

1995 • 435 citations

Midline signalling is required for Pax gene regulation and patterning of the eyes

1995 • 433 citations

T-Brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex

1995 • 415 citations

The Avian Embryo

1999 • 403 citations

Segmental organization of embryonic diencephalon

1993 • 395 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Forebrain patterning defects in Small eye mutant mice

1996 • 379 citations

Mapping of the early neural primordium in quail-chick chimeras

1985 • 378 citations

Mutations affecting the development of the embryonic zebrafish brain

1996 • 374 citations

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

1996 • 369 citations

Emx1andEmx2functions in development of dorsal telencephalon

1997 • 365 citations

Mapping of the early neural primordium in quail-chick chimeras

1987 • 342 citations

Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en

1991 • 339 citations

Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain

1995 • 337 citations

Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants

1994 • 333 citations

Morphogenesis of the murine node and notochordal plate

1994 • 332 citations

Nuclear organization of the bullfrog diencephalon

1983 • 332 citations

Control of cell pattern in the neural tube: Regulation of cell differentiation by dorsalin-1, a novel TGFβ family member

1993 • 320 citations

Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle

1995 • 317 citations

Dorsalization of the neural tube by the non-neural ectoderm

1995 • 295 citations

Order and coherence in the fate map of the zebrafish nervous system

1995 • 292 citations

Caudalization of neural fate by tissue recombination and bFGF

1995 • 290 citations

Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio

1996 • 289 citations

From Egg to Embryo

1983 • 277 citations

Mapping of the presumptive brain regions in the neural plate of Xenopus laevis

1990 • 277 citations

Fates and migratory routes of primitive streak cells in the chick embryo

1996 • 272 citations

Induction of floor plate differentiation by contact-dependent, homeogenetic signals

1993 • 271 citations

A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate

1997 • 270 citations

From Egg to Embryo

1991 • 261 citations

Segment‐related, mosaic neurogenetic pattern in the forebrain and mesencephalon of early chick embryos: I. Topography of ache‐positive neuroblasts up to stage HH18

1987 • 257 citations

Dentate gyrus formation requires Emx2

1996 • 243 citations

The cellular basis of the convergence and extension of the Xenopus neural plate

1992 • 239 citations

An essential role for retinoid signaling in anteroposterior neural patterning

1997 • 236 citations

A fate map of the epiblast of the early chick embryo

1994 • 232 citations

Control of neuronal diversity by the floor plate: Contact-mediated induction of midbrain dopaminergic neurons

1995 • 229 citations

Expression of two zebrafish orthodenticle-related genes in the embryonic brain

1994 • 227 citations

Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain

1994 • 213 citations

Expression of winged helix genes, BF‐1 and BF‐2, define adjacent domains within the developing forebrain and retina

1994 • 208 citations

Model of forebrain regionalization based on spatiotemporal patterns of POU‐III homeobox gene expression, birthdates, and morphological features

1995 • 202 citations

Patterning of the Embryonic Avian Midbrain after Experimental Inversions: A Polarizing Activity from the Isthmus

1994 • 201 citations

Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus

1993 • 200 citations

c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo

1995 • 197 citations

Pax6: more than meets the eye

1995 • 195 citations

Genes involved in forebrain development in the zebrafish, Danio rerio

1996 • 193 citations

The Segmentation of the Primitive Neural Tube in Chick Embryos (Gallus domesticus)

1969 • 185 citations

A Segmental Morphological Paradigm for Understanding Vertebrate Forebrains (Part 1 of 2)

1995 • 184 citations

Uchida rat (rSey): a new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant

1994 • 181 citations

Retinoic acid establishes ventral retinal characteristics

1996 • 178 citations

Clonal Analysis of Cell Fate During Gastrulation and Early Neurulation in the Mouse

2007 • 172 citations

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

1995 • 165 citations

A feulgen-positive nucleolus

1973 • 158 citations

Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1

1995 • 151 citations

Induction of ectopic engrailed expression and fate change in avian rhombomeres: intersegmental boundaries as barriers

1995 • 146 citations

Ectodermal Placodes Contributions to the Development of the Vertebrate Head

1993 • 146 citations

Locations of the ectodermal and nonectodermal subdivisions of the epiblast at stages 3 and 4 of avian gastrulation and neurulation

1993 • 146 citations

The role of the notochord and floor plate in inductive interactions

1995 • 139 citations

Fate of the anterior neural ridge and the morphogenesis of the xenopus forebrain

1995 • 138 citations

Evidence in the mouse for self-renewing stem cells in the formation of a segmented longitudinal structure, the myotome

1996 • 133 citations

1 Homeobox Gene Expression during Development of the Vertebrate Brain

1994 • 131 citations

Gametic imprinting in maize in relation to the angiosperm life cycle

1990 • 126 citations

The determination and positioning of the nose, lens and ear. I. Interactions within the ectoderm, and between the ectoderm and underlying tissues

1963 • 126 citations

XASH-3, a novel Xenopus achaete-scute homolog, provides an early marker of planar neural induction and position along the mediolateral axis of the neural plate

1993 • 125 citations

Planar induction of convergence and extension of the neural plate by the organizer of Xenopus

1992 • 123 citations

Morphogenetic Movements and Fate Maps of Vertebrates

1981 • 123 citations

A Segmental Map of Architectonic Subdivisions in the Diencephalon of the Frog <i>Rana perezi: </i>Acetylcholinesterase-Histochemical Observations; pp. 279–289

1996 • 122 citations

Planar and vertical induction of anteroposterior pattern during the development of the amphibian central nervous system

1993 • 120 citations

Visual projection map specified by topographic expression of transcription factors in the retina

1996 • 118 citations

Vertebrate eye development

1992 • 118 citations

Localization of the prospective neural plate in the early chick blastoderm

1952 • 115 citations

Pattern formation in the vertebrate neural plate

1994 • 114 citations

Function of the Eph-related kinase rtk1 in patterning of the zebrafish forebrain

1996 • 113 citations

Independent assignment of antero-posterior and dorso-ventral positional values in the developing chick hindbrain

1995 • 109 citations

Disruption of local retinoid-mediated gene expression accompanies abnormal development in the mammalian olfactory pathway

1997 • 103 citations

Mutation of theEmx-1Homeobox Gene Disrupts the Corpus Callosum

1996 • 103 citations

Neuroectodermal fate of epiblast cells in the distal region of the mouse egg cylinder: implication for body plan organization during early embryogenesis

1995 • 99 citations

Midline signaling in the primordium of the zebrafish anterior central nervous system.

1994 • 98 citations

Patterns of Gene Expression in the Neural Plate and Neural Tube Subdivide the Embryonic Forebrain into Transverse and Longitudinal Domains

1997 • 97 citations

The influence of the olfactory placode on the development of the telencephalon inXenopus laevis

1992 • 94 citations

Homotopic and heterotopic transplantations of quail tectal primordia in chick embryos: Organization of the retinotectal projections in the chimeric embryos

1984 • 89 citations

A homeobox gene involved in node, notochord and neural plate formation of chick embryos

1995 • 85 citations

The Localization of the Presumptive Cerebral Regions in the Neural Plate of the Axolotl Larva

1959 • 80 citations

Extra-Toes (Xt) Homozygous Mutant Mice Demonstrate a Role for the Gli-3 Gene in the Development of the Forebrain

1994 • 77 citations

Evidence that hypophysis and hypothalamus constitute a single entity from the primary stage of histogenesis

1992 • 73 citations

Fate mapping the avian neural plate with quail/chick chimeras: Origin of prospective median wedge cells

1989 • 67 citations

Slow intermixing of cells during Xenopus embryogenesis contributes to the consistency of the blastomere fate map

1989 • 64 citations

Clonal Analysis and Cell Lineages of the Vertebrate Central Nervous System

1985 • 64 citations

The Role of Competence in the Cranio‐Caudal Segregation of the Central Nervous System

1990 • 63 citations

Specification of neurepithelium and surface epithelium in avian transplantation chimeras

1991 • 56 citations

Fate mapping the neural plate and the intraembryonic mesoblast in the upper layer of the chicken blastoderm with xenografting and time-lapse videography

1992 • 48 citations

Ontogenesis of hypothalamic immunoreactive ACTH cells in vivo and in vitro: Role of Rathke's pouch

1983 • 43 citations

Location of the rostral end of the longitudinal brain axis: Review of an old topic in the light of marking experiments on the closing rostral neuropore

1987 • 42 citations

Primitivstreifen und Urk�rper nach St�rungs versuchen am 1?2 tage bebr�teten H�hnchen

1936 • 40 citations

The quantitative relationship between olfactory axons and mitral/tufted cells in developing Xenopus with partially deafferented olfactory bulbs

1993 • 39 citations

Shaping and bending of the avian neural plate as analysed with a fluorescent-histochemical marker

1989 • 36 citations

Morphological and mapping studies of the paranodal and postnodal levels of the neural plate during chick neurulation

1992 • 32 citations

Hensen's node — The ’Organizer’ of the amniote embryo

1976 • 29 citations

A re-examination of mitotic activity in the early chick embryo

1979 • 28 citations

Regulation of patterning and differentiation in the embryonic vertebrate forebrain

1998 • 27 citations

Something's fishy here—rethinking cell movements and cell fate in the zebrafish embryo

1993 • 25 citations

Experimental Analyses of the Shaping of the Neural Plate and Tube

1991 • 22 citations

Disruption of local retinoid‐mediated gene expression accompanies abnormal development in the mammalian olfactory pathway

1997 • 10 citations

Developmental neurobiology of the anterior areas in amphibians: urodele perspectives.

1996 • 10 citations

Methods for Clonal Analysis and Tracing Cell Lineages of Vertebrate Central Nervous System

1990 • 1 citations