Laboratory methods of diagnosis of syphilis for the beginning of the third millennium

Complete Genome Sequence of Treponema pallidum , the Syphilis Spirochete

1998 • 1,060 citations

Laboratory diagnosis and interpretation of tests for syphilis

1995 • 715 citations

Invasion of the Central Nervous System by Treponema pallidum: Implications for Diagnosis and Treatment

1988 • 577 citations

Alteration in the Natural History of Neurosyphilis by Concurrent Infection with the Human Immunodeficiency Virus

1987 • 563 citations

A Randomized Trial of Enhanced Therapy for Early Syphilis in Patients with and without Human Immunodeficiency Virus Infection

1997 • 532 citations

Global prevalence and incidence estimates of selected curable STDs.

1998 • 529 citations

IMMOBILIZATION OF TREPONEMA PALLIDUM IN VITRO BY ANTIBODY PRODUCED IN SYPHILITIC INFECTION

1949 • 386 citations

Eine serodiagnostische Reaktion bei Syphilis

1906 • 362 citations

Effect of Human Immunodeficiency Virus (HIV) Infection on the Course of Syphilis and on the Response to Treatment

1990 • 353 citations

Neurologic Relapse after Benzathine Penicillin Therapy for Secondary Syphilis in a Patient with HIV Infection

1987 • 345 citations

Simultaneous PCR detection of Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus types 1 and 2 from genital ulcers

1996 • 312 citations

Serologic Response to Treatment of Infectious Syphilis

1991 • 251 citations

A New Serologically Active Phospholipid from Beef Heart

1941 • 251 citations

The Oslo Study of the Natural Course of Untreated Syphilis: An Epidemiologic Investigation Based on a Re-study of the Boeck-Bruusgaard Material

1964 • 223 citations

Sensitive detection of Treponema pallidum by using the polymerase chain reaction

1991 • 208 citations

An Improved FTA Test for Syphilis, the Absorption Procedure (FTA-ABS)

1964 • 204 citations

Molecular Subtyping of Treponema pallidum Subspecies pallidum

1998 • 191 citations

History of Syphilis

1992 • 175 citations

Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid

1991 • 173 citations

The Oslo study of untreated syphilis; an epidemiologic investigation of the natural course of the syphilitic infection based upon a re-study of the Boeck-Bruusgaard material.

1955 • 155 citations

Congenital Syphilis Presenting in Infants after the Newborn Period

1990 • 145 citations

Evaluation of Molecular Methodologies and Rabbit Infectivity Testing for the Diagnosis of Congenital Syphilis and Neonatal Central Nervous System Invasion by Treponema pallidum

1993 • 144 citations

The minimal infectious inoculum of Spirochaeta pallida (Nichols strain) and a consideration of its rate of multiplication in vivo.

1948 • 140 citations

Detection by polymerase chain reaction of Treponema pallidum DNA in cerebrospinal fluid from neurosyphilis patients before and after antibiotic treatment

1991 • 135 citations

Detection of Treponema pallidum by a sensitive reverse transcriptase PCR

1997 • 114 citations

Sensitivity of Treponemal Tests for Detecting Prior Treated Syphilis during Human Immunodeficiency Virus Infection

1990 • 114 citations

Elimination of Syphilis in the United States

1998 • 113 citations

Phospholipid-Binding Antibodies

2020 • 109 citations

Serological response to syphilis treatment. A new analysis of old data.

1985 • 103 citations

Novel Recombinant-Antigen Enzyme Immunoassay for Serological Diagnosis of Syphilis

1998 • 97 citations

Serologic Response to Treatment of Syphilis in Patients With HIV Infection

1996 • 93 citations

Serological Response to Syphilis Treatment

1985 • 89 citations

Evaluation of the Captia enzyme immunoassays for detection of immunoglobulins G and M to Treponema pallidum in syphilis

1990 • 88 citations

Molecular Analysis of the Fetal IgM Response to Treponema pallidum Antigens: Implications for Improved Serodiagnosis of Congenital Syphilis

1989 • 82 citations

Use of the polymerase chain reaction to detect DNA sequences specific to pathogenic treponemes in cerebrospinal fluid

1990 • 79 citations

Cerebral Syphilitic Gumma Confirmed by the Polymerase Chain Reaction in a Man with Human Immunodeficiency Virus Infection

1994 • 74 citations

A microflocculation test for syphilis using cardiolipin antigen; preliminary report.

1946 • 71 citations

Syphilis: New Diagnostic Directions

1992 • 67 citations

ASYMPTOMATIC NEUROSYPHILIS

1930 • 65 citations

Evaluation of a Treponema pallidum western immunoblot assay as a confirmatory test for syphilis

1992 • 64 citations

Fluorescent Treponemal-Antibody Absorption Tests

1967 • 62 citations

Detection of Treponema pallidum by a Fluorescent Monoclonal Antibody Test

1987 • 60 citations

Sensitivity and specificity of an enzyme-linked immunosorbent assay using the recombinant DNA-derived Treponema pallidum protein TmpA for serodiagnosis of syphilis and the potential use of TmpA for assessing the effect of antibiotic therapy

1989 • 59 citations

Enzyme immunoassay for anti-treponemal IgG: screening or confirmatory test?

1992 • 58 citations

Clinical and Serologic Evaluation of Neonates for Congenital Syphilis: A Continuing Diagnostic Dilemma

1993 • 58 citations

Vorläufiger Bericht über das Vorkommen von Spirochaeten in syphilitischen Krankheitsprodukten und bei Papillomen

1978 • 58 citations

Recognition of Treponema pallidum Antigens by IgM and IgG Antibodies in Congenitally Infected Newborns and Their Mothers

1988 • 57 citations

Detection of Treponema pallidum in early syphilis by DNA amplification

1992 • 57 citations

Evaluation of immunoglobulin M western blot analysis in the diagnosis of congenital syphilis

1990 • 54 citations

SHORT COMMUNICATION

1991 • 53 citations

Guidelines for the prevention and control of congenital syphilis.

1988 • 43 citations

Identification of Persistent Infection in Experimental Syphilis by PCR

1998 • 42 citations

Screening for treponemal infection by a new enzyme immunoassay.

1989 • 42 citations

The Standardization of the Cardiolipin-Lecithin-Cholesterol Antigen in the Complement-Fixation Test for Syphilis

1945 • 38 citations

Solid-hase hemadsorption: a method for rapid detection of Treponema pallidum-specific IgM.

1980 • 38 citations

Enzyme-linked immunosorbent assay for detection of antibodies to the venereal disease research laboratory (VDRL) antigen in syphilis

1987 • 36 citations

Evaluation of a New Competitive Immunoassay (BioElisa Syphilis) for Screening for Treponema pallidum Antibodies at Various Stages of Syphilis

1998 • 35 citations

Pathology of the umbilical cord in congenital syphilis: Analysis of 25 specimens using histochemistry and immunofluorescent antibody to Treponema pallidum

1995 • 34 citations

Specific direct fluorescent antibody detection of Treponema pallidum.

1977 • 34 citations

Solid-phase Hemadsorption

1980 • 31 citations

Differences in functional activity of anticardiolipin antibodies from patients with syphilis and those with antiphospholipid syndrome

1994 • 31 citations

Comparison of CAPTIA syphilis G enzyme immunoassay with rapid plasma reagin test for detection of syphilis

1995 • 30 citations

Analysis of western blotting (immunoblotting) technique in diagnosis of congenital syphilis

1994 • 26 citations

Use of the Treponema pallidum-specific captia syphilis IgG assay in conjunction with the rapid plasma reagin to test for syphilis

1997 • 24 citations

Markers of Past Syphilis in HIV Infection Comparing Captia Syphilis G Anti-Treponemal IgG Enzyme Immunoassay with other Treponemal Antigen Tests

1995 • 23 citations

Immunology and pathogenesis of syphilis

1992 • 22 citations

An IgM capture enzyme linked immunosorbent assay to detect IgM antibodies to treponemes in patients with syphilis.

1989 • 20 citations

Primary and Secondary Syphilis--United States, 1997

1998 • 20 citations

Target organs of infection in guinea pigs with acquired congenital syphilis

1996 • 18 citations

Extensive Cross Reactivity between <i>Treponema pallidum</i> and Cultivable Treponemes Demonstrated by Sequential Immunoadsorption

1986 • 16 citations

An analysis of false positive reactions occurring with the Captia Syph G EIA.

1991 • 14 citations

Pathogen-Specific Humoral Response in Treponema pallidum-Infected Humans, Rabbits, and Guinea Pigs

1991 • 14 citations

Evaluation of the DCL Syphilis-G Enzyme Immunoassay Test Kit for the Serologic Diagnosis of Syphilis

1993 • 13 citations

Clinical and diagnostic issues of acquired and congenital syphilis encompassed in the current syphilis epidemic

1993 • 13 citations

Fluorescent Treponemal Antibody‐Absorption (FTA‐ABS) Test

1982 • 12 citations

Rheumatoid factor in congenital syphilis.

1989 • 10 citations

Relationship of antibodies detected by the immunofluorescence method with the various classes of immunoglobulins in cases of untreated syphilis.

1970 • 9 citations

Visuwell Reagin, a non-treponemal enzyme-linked immunosorbent assay for the serodiagnosis of syphilis

1989 • 9 citations

Anti-Treponema pallidum IgM, IgA, and IgG subclass antibody responses after treatment in patients with syphilis at various stages: 1. Assessments by enzyme-linked immunosorbent assay.

1990 • 8 citations

Capture-S, a nontreponemal solid-phase erythrocyte adherence assay for serological detection of syphilis

1997 • 6 citations