Evaluation of Molecular Methodologies and Rabbit Infectivity Testing for the Diagnosis of Congenital Syphilis and Neonatal Central Nervous System Invasion by Treponema pallidum

Avoiding false positives with PCR

1989 • 3,564 citations

BMPD statistical software manual

1988 • 2,605 citations

Infectious Diseases of the Fetus and Newborn Infant

1984 • 2,479 citations

The measurement of interrater agreement

1981 • 689 citations

Invasion of the Central Nervous System by Treponema pallidum: Implications for Diagnosis and Treatment

1988 • 577 citations

Sensitive detection of Treponema pallidum by using the polymerase chain reaction

1991 • 208 citations

Cerebrospinal fluid evaluation in neonates: Comparison of high-risk infants with and without meningitis

1976 • 207 citations

Identification and localization of integral membrane proteins of virulent Treponema pallidum subsp. pallidum by phase partitioning with the nonionic detergent triton X-114

1988 • 179 citations

Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid

1991 • 173 citations

Congenital Syphilis Presenting in Infants after the Newborn Period

1990 • 145 citations

Major integral membrane protein immunogens of Treponema pallidum are proteolipids

1989 • 143 citations

Novel low-molecular-weight synthetic vaccine against foot-and-mouth disease containing a potent B-cell and macrophage activator

1989 • 140 citations

The minimal infectious inoculum of Spirochaeta pallida (Nichols strain) and a consideration of its rate of multiplication in vivo.

1948 • 140 citations

Detection by polymerase chain reaction of Treponema pallidum DNA in cerebrospinal fluid from neurosyphilis patients before and after antibiotic treatment

1991 • 135 citations

The Incidence of Prenatal Syphilis at the Boston City Hospital

1952 • 123 citations

Purification of Treponema pallidum, Nichols Strain, by Percoll Density Gradient Centrifugation

1984 • 107 citations

Subclinical central nervous system disease of neonates: A prospective study of infants born with increased levels of IgM

1969 • 91 citations

Murine monoclonal antibodies specific for virulent Treponema pallidum (Nichols)

1982 • 85 citations

Congenital Syphilis Revisited

1985 • 83 citations

Molecular Analysis of the Fetal IgM Response to Treponema pallidum Antigens: Implications for Improved Serodiagnosis of Congenital Syphilis

1989 • 82 citations

Use of the polymerase chain reaction to detect DNA sequences specific to pathogenic treponemes in cerebrospinal fluid

1990 • 79 citations

Identification of Treponema pallidum in amniotic fluid and fetal blood from pregnancies complicated by congenital syphilis.

1991 • 78 citations

PASSIVE TRANSFER OF ANTIBODIES OF MATERNAL ORIGIN FROM BLOOD TO CEREBROSPINAL FLUID IN INFANTS

1975 • 77 citations

Evaluation and treatment of congenital syphilis

1990 • 76 citations

Infectivity tests in syphilis.

1969 • 69 citations

Characterization of the antigenic determinants and host components in immune complexes from patients with secondary syphilis.

1986 • 59 citations

Detection of treponemal DNA in the CSF of patients with syphilis and HIV infection using the polymerase chain reaction.

1990 • 59 citations

Recognition of Treponema pallidum Antigens by IgM and IgG Antibodies in Congenitally Infected Newborns and Their Mothers

1988 • 57 citations

Detection of Treponema pallidum in early syphilis by DNA amplification

1992 • 57 citations

Congenital syphilis: trends and recommendations for evaluation and management.

1991 • 55 citations

The FTA-ABS (IgM) test for neonatal congenital syphilis: A critical review.

1974 • 53 citations

Pathogen specificity of Treponema pallidum subsp. pallidum integral membrane proteins identified by phase partitioning with Triton X-114

1988 • 52 citations

Monoclonal antibody analysis of specific antigenic similarities among pathogenic Treponema pallidum subspecies

1984 • 50 citations

Characterization of lipid-modified immunogenic proteins of Treponema pallidum expressed in Escherichia coli

1989 • 46 citations

Congenital syphilis

1983 • 37 citations

Cerebrospinal fluid levels of benzathine penicillin G in the neonate

1977 • 37 citations

Burstain JM, Grimprel E, Lukehart SA, Norgard MV, Radolf JDSensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol 29:62-69

1991 • 27 citations

Clinical pharmacology of benzatbine penicillin G in neonates with regard to its recommended use in congenital syphilis

1973 • 24 citations

Congenital syphilis. Serologic diagnosis in the young infant.

1992 • 23 citations

Characterization of the Components in Circulating Immune Complexes from Infants with Congenital Syphilis

1988 • 21 citations

Immunogenicity of lipid-conjugated antigens. I. The influence of chain length and degree of conjugation on induction of antibody in mice.

1980 • 13 citations

TREATMENT OF CONGENITAL SYPHILIS

1934 • 7 citations