Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera, and cerebrospinal fluid

Avoiding false positives with PCR

1989 • 3,564 citations

Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction

1989 • 895 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Simple and Rapid Preparation of Samples for PCR

1989 • 596 citations

Invasion of the Central Nervous System by Treponema pallidum: Implications for Diagnosis and Treatment

1988 • 577 citations

Detection of Epstein-Barr virus DNA by polymerase chain reaction in blood and tissue biopsies from patients with Sjogren's syndrome.

1989 • 409 citations

Detection of Trypanosoma cruzi by DNA amplification using the polymerase chain reaction

1989 • 407 citations

RAPID DIAGNOSIS OF TUBERCULOSIS BY AMPLIFICATION OF MYCOBACTERIAL DNA IN CLINICAL SAMPLES

1989 • 406 citations

Detection and identification of mycobacteria by amplification of mycobacterial DNA

1989 • 313 citations

Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid

1990 • 236 citations

Detection of Mycoplasma pneumoniae by using the polymerase chain reaction

1989 • 212 citations

Sensitive detection of Treponema pallidum by using the polymerase chain reaction

1991 • 208 citations

A Correlative Immunologic, Microbiologic and Clinical Approach to the Diagnosis of Acute and Chronic Infections in Newborn Infants

1967 • 161 citations

Congenital Syphilis Presenting in Infants after the Newborn Period

1990 • 145 citations

The minimal infectious inoculum of Spirochaeta pallida (Nichols strain) and a consideration of its rate of multiplication in vivo.

1948 • 140 citations

Subclinical central nervous system disease of neonates: A prospective study of infants born with increased levels of IgM

1969 • 91 citations

Detection of Borrelia burgdorferi using the polymerase chain reaction

1990 • 83 citations

Congenital Syphilis Revisited

1985 • 83 citations

Molecular Analysis of the Fetal IgM Response to Treponema pallidum Antigens: Implications for Improved Serodiagnosis of Congenital Syphilis

1989 • 82 citations

Use of the polymerase chain reaction to detect DNA sequences specific to pathogenic treponemes in cerebrospinal fluid

1990 • 79 citations

Identification of Treponema pallidum in amniotic fluid and fetal blood from pregnancies complicated by congenital syphilis.

1991 • 78 citations

Use of Polymerase Chain Reaction for Successful Identification of Asymptomatic Genital Infection with Herpes Simplex Virus in Pregnant Women at Delivery

1990 • 71 citations

Infectivity tests in syphilis.

1969 • 69 citations

INCIDENCE OF SPIROCHAETA PALLIDA IN CEREBROSPINAL FLUID DURING EARLY STAGE OF SYPHILIS

1924 • 62 citations

Questionnaire Survey of Reported Early Congenital Syphilis

1977 • 60 citations

Recognition of Treponema pallidum Antigens by IgM and IgG Antibodies in Congenitally Infected Newborns and Their Mothers

1988 • 57 citations

Evaluation of immunoglobulin M western blot analysis in the diagnosis of congenital syphilis

1990 • 54 citations

The FTA-ABS (IgM) test for neonatal congenital syphilis: A critical review.

1974 • 53 citations

Quantitation of cord serum IgM and IgA as a screening procedure to detect congenital infection: Results in 5,006 infants

1969 • 51 citations

Serum immunoglobulin levels in newborn infants. II. Survey of cord and follow-up sera from 123 infants with congenital rubella

1969 • 49 citations

Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum

1989 • 48 citations

Examination of amniotic fluid in diagnosing congenital syphilis with fetal death

1990 • 38 citations

Congenital syphilis

1983 • 37 citations

Immunoglobulin M determinations in neonates and infants as an adjunct to the diagnosis of infection

1969 • 23 citations

Neonatal IgM response to acute infection

1969 • 18 citations

Congenital syphilis: Observations on laboratory diagnosis of intrauterine infection

1969 • 12 citations

CONGENITAL SYPHILIS

1935 • 11 citations

Diagnostic Considerations in lntra-amniotic Syphilis

1985 • 8 citations

Immunologic response of the fetus in congenital syphilis.

1969 • 5 citations