Complete Genome Sequence of Treponema pallidum , the Syphilis Spirochete

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

1995 • 5,571 citations

The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications

1987 • 3,628 citations

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

1997 • 2,082 citations

Pfam: A comprehensive database of protein domain families based on seed alignments

1997 • 1,211 citations

Microbial gene identification using interpolated Markov models

1998 • 1,000 citations

Ion motive ATPases. I. Ubiquity, properties, and significance to cell function

1987 • 964 citations

Asymmetric substitution patterns in the two DNA strands of bacteria

1996 • 741 citations

Structure and function of vacuolar class of ATP-driven proton pumps

1989 • 600 citations

Phylogenetic analysis of the spirochetes

1991 • 349 citations

Functions of the gene products of Escherichia coli

1993 • 330 citations

Strand asymmetries in DNA evolution

1997 • 257 citations

ATP-dependent protein kinase-catalyzed phosphorylation of a seryl residue in HPr, a phosphate carrier protein of the phosphotransferase system in Streptococcus pyogenes.

1983 • 237 citations

Outer membrane ultrastructure explains the limited antigenicity of virulent Treponema pallidum.

1989 • 209 citations

NOVEL PROTEINS OF THE PHOSPHOTRANSFERASE SYSTEM ENCODED WITHIN THE RPON OPERON OF ESCHERICHIA-COLI - ENZYME IIA(NTR) AFFECTS GROWTH ON ORGANIC NITROGEN AND THE CONDITIONAL LETHALITY OF AN ERA(TS) MUTANT

1995 • 208 citations

A novel protein kinase that controls carbon catabolite repression in bacteria

1998 • 206 citations

The bacterial phosphotransferase system: new frontiers 30 years later

1994 • 197 citations

A Euryarchaeal Lysyl-tRNA Synthetase: Resemblance to Class I Synthetases

1997 • 194 citations

Novel Proteins of the Phosphotransferase System Encoded within the rpoN Operon of Escherichia coli

1995 • 184 citations

Adaptation to life at micromolar nutrient levels: the regulation ofEscherichia coliglucose transport by endoinduction and cAMP

1996 • 167 citations

Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Treponema Pallidum Polypeptide Research Group

1993 • 161 citations

Binding of the Catabolite Repressor Protein CcpA to Its DNA Target Is Regulated by Phosphorylation of its Corepressor HPr

1997 • 145 citations

Sequence analysis, expression, and binding activity of recombinant major outer sheath protein (Msp) of Treponema denticola

1996 • 143 citations

The crystal structures of T. thermophilus lysyl-tRNA synthetase complexed with E. coli tRNA(Lys) and a T. thermophilus tRNA(Lys) transcript: anticodon recognition and conformational changes upon binding of a lysyl-adenylate analogue.

1996 • 141 citations

Mechanistic and physiological consequences of HPr(ser) phosphorylation on the activities of the phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: studies with site-specific mutants of HPr.

1989 • 141 citations

The outer membrane, not a coat of host proteins, limits antigenicity of virulent Treponema pallidum

1992 • 134 citations

Isolation and characterization of a pyrophosphate-dependent phosphofructokinase from Propionibacterium shermanii.

1975 • 131 citations

Pathogenesis and immunology of treponemal infection

1983 • 110 citations

Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae

1994 • 107 citations

Spirochete chemotaxis, motility, and the structure of the spirochetal periplasmic flagella

1992 • 107 citations

Enhanced translational motion of Leptospira in viscous environments

1975 • 106 citations

Treponema pallidum and the quest for outer membrane proteins

1995 • 104 citations

The sodium ion translocating oxalacetate decarboxylase of Klebsiella pneumoniae. Sequence of the biotin-containing alpha-subunit and relationship to other biotin-containing enzymes.

1988 • 97 citations

DEMONSTRATION OF SPIROCHAETA PALLIDA IN THE CEREBROSPINAL FLUID

1913 • 93 citations

Archaeal-type lysyl-tRNA synthetase in the Lyme disease spirochete Borrelia burgdorferi

1997 • 89 citations

A proposed link between nitrogen and carbon metabolism involving protein phosphorylation in bacteria

1992 • 88 citations

Cultivation of Virulent Treponema pallidum in Tissue Culture

1981 • 86 citations

The major surface protein complex of Treponema denticola depolarizes and induces ion channels in HeLa cell membranes

1996 • 85 citations

Antigenic relatedness and N-terminal sequence homology define two classes of periplasmic flagellar proteins of Treponema pallidum subsp. pallidum and Treponema phagedenis

1988 • 83 citations

Heat shock response of spirochetes

1991 • 83 citations

Conservation of gene arrangement and an unusual organization of rRNA genes in the linear chromosomes of the Lyme disease spirochaetes Borrelia burgdorferi, B. garinii and B. afzelii

1994 • 81 citations

Analysis of outer membrane ultrastructure of pathogenic Treponema and Borrelia species by freeze-fracture electron microscopy

1991 • 78 citations

Purification and properties of the ATphase Solubilized from Membranes of an Acidothermophilic Archaeobacterium, sulfolobus acidocaldarius1

1987 • 74 citations

Conservation of msp, the gene encoding the major outer membrane protein of oral Treponema spp

1997 • 73 citations

Gene structure of Enterococcus hirae (Streptococcus faecalis) F1F0-ATPase, which functions as a regulator of cytoplasmic pH

1992 • 63 citations

Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum

1989 • 57 citations

Oxygen Uptake by Treponema pallidum

1974 • 52 citations

Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1)

1995 • 52 citations

The importance of the binding-protein-dependent Mgl system to the transport of glucose in Escherichia coli growing on low sugar concentrations

1993 • 52 citations

Culture of Treponema pallidum

1994 • 48 citations

Solution Structure of the Anticodon-binding Domain of Escherichia coli Lysyl-tRNA Synthetase and Studies of its Interaction with tRNALys

1995 • 46 citations

Pyrophosphate-dependent phosphofructokinase of Entamoeba histolytica: molecular cloning, recombinant expression and inhibition by pyrophosphate analogues

1996 • 45 citations

Molecules and mental illness

1993 • 45 citations

Effects of molecular oxygen, oxidation-reduction potential, and antioxidants upon in vitro replication of Treponema pallidum subsp. pallidum

1990 • 44 citations

Tromp1, a putative rare outer membrane protein, is anchored by an uncleaved signal sequence to the Treponema pallidum cytoplasmic membrane

1997 • 43 citations

Surface Antigens of the Syphilis Spirochete and Their Potential as Virulence Determinants

1997 • 43 citations

Treponema pallidum subsp. pallidum has a single, circular chromosome with a size of approximately 900 kilobase pairs

1991 • 42 citations

Purification of Treponema pallidum from Infected Rabbit Tissue: Resolution into Two Treponemal Populations

1974 • 42 citations

Prokaryotic Genome Evolution as Assessed by Multivariate Analysis of Codon Usage Patterns

1997 • 33 citations

Molecular characterization of a flagellar/chemotaxis operon in the spirochete Borrelia burgdorferi

2006 • 31 citations

Physical map of the genome of Treponema pallidum subsp. pallidum (Nichols)

1995 • 31 citations

Morphological destruction of cultured cells by the attachment of Treponema pallidum.

1982 • 28 citations

Organization, transcription, and expression of the 5' region of the fla operon of Treponema phagedenis and Treponema pallidum

1996 • 26 citations

Cloning and analysis of a Borrelia burgdorferi membrane‐interactive protein exhibiting haemolytic activity

1997 • 24 citations

The Microaerophilic Nature of Treponema pallidurn

1982 • 23 citations

Respiration and Oxidative Phosphorylation in Treponema pallidum

1978 • 21 citations

Two 16S-23S ribosomal DNA intergenic regions in different Treponema pallidum subspecies contain tRNA genes

1996 • 21 citations

Evidence for a methyl-accepting chemotaxis protein gene (mcp1) that encodes a putative sensory transducer in virulent Treponema pallidum

1997 • 21 citations

Pyrophosphate-dependent phosphofructo-1-kinase complements fructose 1,6-bisphosphatase but not phosphofructokinase deficiency in Escherichia coli

1993 • 18 citations

A mgl-like operon in Treponema pallidum, the syphilis spirochete

1996 • 18 citations

Albumin requirement of Treponema denticola and Treponema vincentii

1983 • 16 citations

Gene therapy for myocardial ischemia (FJ Giordano et al, US)

1997 • 16 citations

Distribution of glucose incorporated into macromolecular material by treponema pallidum

1981 • 16 citations

Aerobic Spirochetes: The Genus Leptospira

1981 • 15 citations

Identification, Sequences, and Expression ofTreponema pallidumChemotaxis Genes

1997 • 15 citations

Identification and characterization of a Treponema pallidum subsp. pallidum gene encoding a DNA adenine methyltransferase

2006 • 11 citations

Inhibition of macromolecular synthesis in cultured rabbit cells by Treponema pallidum (Nichols)

1983 • 10 citations

Identification and sequences of theTreponema pallidum mglAandmglCgenes

1996 • 8 citations

Inhibition by Thiamine Phosphates of Thiamine Uptake in Escherichia coli

1972 • 7 citations