CD4 expression is differentially required for deletion of MLS-1a-reactive T cells.

Superantigens: Mechanism of T-Cell Stimulation and Role in Immune Responses

1991 • 783 citations

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1991 • 695 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

Superantigens interact with MHC class II molecules outside of the antigen groove

1990 • 438 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus

1991 • 277 citations

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

1988 • 265 citations

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1990 • 242 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

A standardized nomenclature for endogenous mouse mammary tumor viruses

1987 • 136 citations

Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.

1990 • 124 citations

Antioncogenic effect of adenovirus E1A in human tumor cells.

1991 • 112 citations

Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor.

1988 • 100 citations

Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirus Mtv-7.

1992 • 83 citations

T‐Cell Reactivity and Tolerance to Mls^a‐Encoded Antigens

1989 • 62 citations

Characterization of endogenous and exogenous mouse mammary tumor virus proviral DNA with site-specific molecular clones

1980 • 61 citations

Differential reactivity of V_β9 T cells to minor lymphocyte stimulating antigen in vitro and in vivo

1991 • 55 citations

Response of mature unprimed CD8+ T cells to Mlsa determinants.

1990 • 47 citations

CD8+ T cells respond clonally to Mls-1a-encoded determinants.

1990 • 41 citations

Analysis of T cell receptor V_β gene usage in primary mixed lymphocyte reactions : evidence for directive usage by different antigen‐presenting cells and Mls‐like determinants on T cell blasts

1990 • 25 citations

Hierarchy of responsiveness in vivo and in vitro among T cells expressing distinct MIs‐1^a‐reactive V_β domains

1992 • 23 citations

CD8+ T cell response to Mls-1a determinants involves major histocompatibility complex class II molecules.

1991 • 19 citations