Analysis of T cell receptor V_β gene usage in primary mixed lymphocyte reactions : evidence for directive usage by different antigen‐presenting cells and Mls‐like determinants on T cell blasts

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells

1989 • 706 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro.

1979 • 514 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors.

1977 • 357 citations

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells.

1989 • 331 citations

H—2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide

1986 • 252 citations

Direct activation of CD8+ cytotoxic T lymphocytes by dendritic cells.

1987 • 237 citations

Implications of a Fab-like structure for the T-cell receptor

1989 • 193 citations

Peptide-dependent recognition of H–2Kb by alloreactive cytotoxic T lymphocytes

1989 • 168 citations

U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs

1986 • 160 citations

High frequency and nonrandom distribution of alloreactivity in T cell clones selected for recognition of foreign antigen in association with self class II molecules.

1986 • 158 citations

Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event.

1981 • 153 citations

MHC-Antigen Interaction: What Does the T Cell Receptor See?

1989 • 102 citations

Distinct features of dendritic cells and anti-Ig activated B cells as stimulators of the primary mixed leukocyte reaction.

1989 • 96 citations

Restricted tissue distribution of Mlsa determinants. Stimulation of Mlsa-reactive T cells by B cells but not by dendritic cells or macrophages.

1989 • 90 citations

Cytotoxic T cell clone‐specific monoclonal antibodies used to select clonotypic antigen‐specific cytotoxic T cells

1985 • 90 citations

Enumeration of IL 2-secreting helper T cells by limiting dilution analysis, and demonstration of unexpectedly high levels of IL 2 production per responding cell.

1982 • 77 citations

Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen‐presenting cells

1989 • 76 citations

Allospecific cytotoxic T lymphocytes recognize an H-2 peptide in the context of a murine major histocompatibility complex class I molecule.

1988 • 68 citations

Relative V beta transcript levels in thymus and peripheral lymphoid tissues from various mouse strains. Inverse correlation of I-E and Mls expression with relative abundance of several V beta transcripts in peripheral lymphoid tissues.

1989 • 65 citations

T cell responses to Mls determinants are restricted by cross-reactive MHC determinants.

1985 • 60 citations

Heterogeneity of stimulator cells in the murine mixed leukocyte response

1982 • 57 citations

Analysis of specificity for antigen, Mls, and allogeneic MHC by transfer of T-cell receptor α- and β-chain genes

1988 • 52 citations

Macrophages and T cells do not express Mlsa determinants.

1989 • 47 citations

Enumeration of alloreactive helper T lymphocytes which cooperate with cytolytic T lymphocytes

1981 • 42 citations

Capacity of B cells to function as stimulators of a primary mixed leukocyte reaction.

1986 • 41 citations

Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule.

1988 • 28 citations

STUDIES ON NON‐H‐2 LINKED LYMPHOCYTE ACTIVATING DETERMINANTS I. DESCRIPTION OF THE CELL TYPE BEARING THE MLS PRODUCT

1977 • 27 citations

The contribution of mutant amino acids to alloantigenicity.

1989 • 19 citations

Neonatal tolerance induction to Mlsa

1988 • 12 citations

Direct demonstration of critical amino acid residues required for cytotoxic T-lymphocyte allorecognition of H-2 class I antigens.

1988 • 10 citations

Effector functions and specificities of normal murine T cells stimulated by syngeneic blasts

1986 • 9 citations

TCR Vβ genes in man and mouse and the factors that shape the linkage pattern of immune receptor genes

1989 • 6 citations