Hierarchy of responsiveness in vivo and in vitro among T cells expressing distinct MIs‐1^a‐reactive V_β domains

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1989 • 462 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

1991 • 394 citations

Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus

1991 • 277 citations

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

1991 • 263 citations

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1990 • 242 citations

Peripheral Clonal Elimination of Functional T Cells

1990 • 213 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.

1990 • 124 citations

A third T-cell receptor beta-chain variable region gene encodes reactivity to Mls-1a gene products.

1989 • 105 citations

Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor.

1988 • 100 citations

Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.

1991 • 95 citations

Ligand thresholds at different stages of T cell development

1990 • 84 citations

Differential reactivity of V_β9 T cells to minor lymphocyte stimulating antigen in vitro and in vivo

1991 • 55 citations

A characteristic Mls-1a response precedes Mls-1a anergy in vivo.

1991 • 53 citations

BALB.D2-Mlsa-A new congenic mouse strain

1984 • 47 citations

Response of mature unprimed CD8+ T cells to Mlsa determinants.

1990 • 47 citations

CD8+ T cells respond clonally to Mls-1a-encoded determinants.

1990 • 41 citations

Light scatter analysis and sorting of cells activated in mixed leukocyte culture

1982 • 41 citations

Analysis of T cell receptor V_β gene usage in primary mixed lymphocyte reactions : evidence for directive usage by different antigen‐presenting cells and Mls‐like determinants on T cell blasts

1990 • 25 citations

CD8+ T cell response to Mls-1a determinants involves major histocompatibility complex class II molecules.

1991 • 19 citations

How Important Is the Direct Recognition of Polymorphic MHC Residues by TCR in the Generation of the T-cell Repertoire?

1989 • 14 citations