Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens

1988 • 901 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

The T Cell Receptor

1987 • 554 citations

T Cell Selection in the Thymus

1988 • 405 citations

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells.

1985 • 305 citations

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

1987 • 248 citations

Characterization of murine thymocytes with CDS-associated T-cell receptor structures

1987 • 245 citations

Expression and functional significance of the J11d marker on mouse thymocytes.

1987 • 218 citations

The differentiation of T lymphocytes

1974 • 185 citations

Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.

1979 • 173 citations

An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen.

1987 • 145 citations

The differentiation of T lymphocytes. V. Evidence for intrathymic death of most thymocytes.

1979 • 126 citations

Phenotypic and functional properties of murine thymocytes. I. Precursors of cytolytic T lymphocytes and interleukin 2-producing cells are all contained within a subpopulation of "mature" thymocytes as analyzed by monoclonal antibodies and flow microfluorometry

1982 • 114 citations

The selection of the α,β heterodimeric T-cell receptor for antigen

1986 • 100 citations

Renewal and fate in the mammalian thymus: Mechanisms and inferences of thymocytokinetics

1972 • 99 citations

In vitro maturation of immature thymocytes into immunocompetent T cells in the absence of direct thymic influence

1978 • 92 citations

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

1987 • 89 citations

Recognition and Regulation in Cell-Mediated Immunity

1985 • 79 citations

CD4+ murine T cells develop from CD8+ precursors in vivo

1987 • 71 citations

The functional capacity of thymus subpopulations: limit-dilution analysis of all precursors of cytotoxic lymphocytes and of all T cells capable of proliferation in subpopulations separated by the use of peanut agglutinin.

1982 • 67 citations

Thymic factors and T cell maturation in vitro: a comparison of the effects of thymic epithelial cultures with thymic extracts and thymus dependent serum factors.

1979 • 50 citations

Mucosal Immunity: IgA and Polymorphonuclear Neutrophils

1986 • 47 citations

Alloreactive and H-2-restricted Lyt 23 cytotoxic T lymphocytes derive from a common pool of antecedent Lyt 123 precursors.

1980 • 29 citations

PHENOTYPIC CHARACTERIZATION OF EARLY EVENTS OF THYMUS REPOPULATION IN RADIATION BONE MARROW CHIMERAS

1983 • 25 citations

Methods for the production of xenogeneic monoclonal antibodies in murine ascites.

1985 • 22 citations

Class II major histocompatibility complex molecules regulate the development of the T4+T8- inducer phenotype of cultured human thymocytes.

1985 • 19 citations