Fidelity of Uracil-initiated Base Excision DNA Repair in DNA Polymerase β-Proficient and -Deficient Mouse Embryonic Fibroblast Cell Extracts

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Quality Control by DNA Repair

1999 • 1,469 citations

Human DNA Repair Genes

2001 • 1,451 citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

1996 • 790 citations

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

1997 • 779 citations

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

1996 • 775 citations

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1999 • 624 citations

Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis

1996 • 569 citations

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1995 • 552 citations

Two Pathways for Base Excision Repair in Mammalian Cells

1996 • 520 citations

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA

1998 • 474 citations

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

1992 • 428 citations

PCNA binding through a conserved motif

1998 • 383 citations

Mammalian Abasic Site Base Excision Repair

1998 • 369 citations

Post-replicative base excision repair in replication foci

1999 • 337 citations

Involvement of XRCC1 and DNA Ligase III Gene Products in DNA Base Excision Repair

1997 • 328 citations

Uracil-DNA Glycosylase (UNG)-Deficient Mice Reveal a Primary Role of the Enzyme during DNA Replication

2000 • 315 citations

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

1997 • 301 citations

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

1995 • 276 citations

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

1995 • 276 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: Protein mimicry of DNA

1995 • 268 citations

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

1995 • 259 citations

Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase

1996 • 255 citations

Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

2000 • 248 citations

An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining

1997 • 242 citations

Repair Pathways for Processing of 8-Oxoguanine in DNA by Mammalian Cell Extracts

1998 • 238 citations

Different DNA Polymerases Are Involved in the Short- and Long-Patch Base Excision Repair in Mammalian Cells

1998 • 225 citations

Suppression of spontaneous mutagenesis in human cells by DNA base excision–repair

2000 • 215 citations

Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

1999 • 210 citations

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

1996 • 208 citations

Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

2000 • 207 citations

Impairment of Proliferating Cell Nuclear Antigen-dependent Apurinic/Apyrimidinic Site Repair on Linear DNA

1998 • 202 citations

Base excision repair in a network of defence and tolerance

2001 • 196 citations

A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo.

1981 • 188 citations

Mammalian base excision repair by DNA polymerases δ and ε

1998 • 188 citations

5'-Deoxyribose Phosphate Lyase Activity of Human DNA Polymerase ɩ in Vitro

2001 • 186 citations

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.

1989 • 183 citations

Reconstitution of Proliferating Cell Nuclear Antigen-dependent Repair of Apurinic/Apyrimidinic Sites with Purified Human Proteins

1999 • 177 citations

Biphasic Kinetics of the Human DNA Repair Protein MED1 (MBD4), a Mismatch-specific DNA N-Glycosylase

2000 • 170 citations

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

1999 • 168 citations

[11] Purification and domain-mapping of mammalian DNA polymerase β

1995 • 157 citations

Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21

1995 • 151 citations

Efficient removal of uracil from G.U mispairs by themismatch-specific thymine DNA glycosylase from HeLa cells.

1994 • 146 citations

Kinetics of the Action of Thymine DNA Glycosylase

1998 • 143 citations

The α/β fold uracil DNA glycosylases: a common origin with diverse fates

2000 • 135 citations

The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis

1999 • 134 citations

Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene

1993 • 134 citations

DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate

1986 • 125 citations

Separating Substrate Recognition from Base Hydrolysis in Human Thymine DNA Glycosylase by Mutational Analysis

2000 • 125 citations

p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex.

1996 • 121 citations

DNA Polymerase β: Structure−Fidelity Relationship from Pre-Steady-State Kinetic Analyses of All Possible Correct and Incorrect Base Pairs for Wild Type and R283A Mutant

1997 • 119 citations

Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase 1 1Edited by D. C. Rees

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Excision repair and DNA synthesis with a combination of HeLa DNA polymerase beta and DNase V.

1983 • 107 citations

Uracil-Excision DNA Repair

1994 • 96 citations

Role of MED1 (MBD4) Gene in DNA repair and human cancer

2001 • 96 citations

Purification of nuclear and mitochondrial uracil-DNA glycosylase from rat liver. Identification of two distinct subcellular forms

1985 • 87 citations

Characterization of the Escherichia coli uracil-DNA glycosylase.inhibitor protein complex.

1992 • 84 citations

Thermodynamics of Human DNA Ligase I Trimerization and Association with DNA Polymerase β

1998 • 73 citations

Purification and properties of mitochondrial uracil-DNA glycosylase from rat liver

1988 • 73 citations

Kinetic Analysis of Base Substitution Mutagenesis by Transient Misalignment of DNA and by Miscoding

1989 • 70 citations

Kinetics of the uracil-DNA glycosylase/inhibitor protein association. Ung interaction with Ugi, nucleic acids, and uracil compounds.

1993 • 63 citations

Base Substitution Specificity of DNA Polymerase β Depends on Interactions in the DNA Minor Groove

1999 • 57 citations

Gap-filling DNA synthesis by HeLa DNA polymerase alpha in an in vitro base excision DNA repair scheme.

1984 • 56 citations

The Determination of Plasma Nitrite and Nitrate by Capillary Ion Analysis

1995 • 52 citations

Increased spontaneous mutation frequency in human cells expressing the phage PBS2-encoded inhibitor of uracil-DNA glycosylase

2000 • 39 citations

Fidelity and Mutational Specificity of Uracil-initiated Base Excision DNA Repair Synthesis in Human Glioblastoma Cell Extracts

1998 • 34 citations

Fidelity of Eucaryotic DNA Polymerase δ Holoenzyme fromSchizosaccharomyces pombe

2000 • 30 citations

Fidelity of Uracil-initiated Base Excision DNA Repair inEscherichia coli Cell Extracts

2001 • 12 citations

Uracil-initiated base excision DNA repair synthesis fidelity in human colon adenocarcinoma loVo and Escherichia coli cell extracts

2001 • 9 citations

Uracil-DNA glycosylase inhibitor protein : role of carboxylic acid residues and use for measuring the fidelity of uracil-excision DNA repair synthesis in human cell extracts

1998 • 2 citations