Uracil-DNA Glycosylase (UNG)-Deficient Mice Reveal a Primary Role of the Enzyme during DNA Replication

A simple technique for quantitation of low levels of DNA damage in individual cells

1988 • 10,537 citations

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage

1997 • 1,437 citations

DNA glycosylases in the base excision repair of DNA

1997 • 840 citations

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

1999 • 792 citations

DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination

2000 • 700 citations

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

1999 • 624 citations

Oxidative damage to DNA: do we have a reliable biomarker?

1996 • 612 citations

A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA

1996 • 576 citations

Post-replicative base excision repair in replication foci

1999 • 337 citations

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

1997 • 301 citations

Methotrexate-induced misincorporation of uracil into DNA

1980 • 276 citations

Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: Protein mimicry of DNA

1995 • 268 citations

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

1995 • 259 citations

Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase

1996 • 255 citations

Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

1999 • 210 citations

Specific mutator effects of ung (uracil-DNA glycosylase) mutations in Escherichia coli

1982 • 179 citations

Uracil incorporation: A source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome

1978 • 151 citations

Phenotypic Change Caused by Transcriptional Bypass of Uracil in Nondividing Cells

1999 • 113 citations

Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli

1981 • 107 citations

The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair

1991 • 101 citations

Formation of Okazaki fragments in polyoma DNA synthesis caused by misincorporation of uracil

1978 • 96 citations

Oxidative damage to DNA

1995 • 58 citations

Human Uracil-DNA Glycosylase Gene: Sequence Organization, Methylation Pattern, and Mapping to Chromosome 12q23–q24.1

1996 • 40 citations

The mouse uracil-DNA glycosylase gene: isolation of cDNA and genomic clones and mapping ung to mouse chromosome 5

1997 • 10 citations