Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

DNA Repair and Mutagenesis

2006 • 4,725 citations

The Minimal Gene Complement of Mycoplasma genitalium

1995 • 2,499 citations

DNA repair and mutagenesis

1996 • 2,289 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

1997 • 1,233 citations

The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and Their Expression

1996 • 1,132 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate.

1994 • 1,032 citations

A gene map of the human genome.

1996 • 986 citations

Geminin, an Inhibitor of DNA Replication, Is Degraded during Mitosis

1998 • 886 citations

DNA glycosylases in the base excision repair of DNA

1997 • 840 citations

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.

1995 • 804 citations

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

1997 • 779 citations

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

1996 • 775 citations

A Gene Map of the Human Genome

1996 • 737 citations

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1974 • 725 citations

A Physical Map of 30,000 Human Genes

1998 • 723 citations

DNA REPAIR IN EUKARYOTES

1996 • 682 citations

Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair

1995 • 670 citations

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1998 • 550 citations

A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy

1990 • 495 citations

Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases.

1987 • 399 citations

The structural basis of specific base-excision repair by uracil–DNA glycosylase

1995 • 390 citations

A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase.

1991 • 332 citations

Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA.

1994 • 321 citations

A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer

1997 • 316 citations

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

1997 • 301 citations

Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA

1998 • 284 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

1995 • 259 citations

Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase

1998 • 245 citations

Structural Basis for the Excision Repair of Alkylation-Damaged DNA

1996 • 244 citations

Systematic identification of mitotic phosphoproteins

1997 • 225 citations

Involvement of Flap Endonuclease 1 in Base Excision DNA Repair

1998 • 202 citations

Efficient Repair of Abasic Sites in DNA by Mitochondrial Enzymes

1998 • 191 citations

NH2-terminal Proline Acts as a Nucleophile in the Glycosylase/AP-Lyase Reaction Catalyzed by Escherichia coli Formamidopyrimidine-DNA Glycosylase (Fpg) Protein

1997 • 177 citations

3, N ⁴ -ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

1998 • 172 citations

The critical active-site amine of the human 8-oxoguanine DNA glycosylase, hOgg1: direct identification, ablation and chemical reconstitution

1997 • 165 citations

A Sequence in the N-terminal Region of Human Uracil-DNA Glycosylase with Homology to XPA Interacts with the C-terminal Part of the 34-kDa Subunit of Replication Protein A

1997 • 146 citations

Kinetics of the Action of Thymine DNA Glycosylase

1998 • 143 citations

Studies on the Catalytic Mechanism of Five DNA Glycosylases

1995 • 142 citations

Purification and characterization of human 3-methyladenine-DNA glycosylase

1993 • 136 citations

No "End of History" for Photolyases

1996 • 128 citations

Specific Proteolysis of the Kinase Protein Kinase C-related Kinase 2 by Caspase-3 during Apoptosis

1997 • 103 citations

Specific Binding of a Designed Pyrrolidine Abasic Site Analog to Multiple DNA Glycosylases

1998 • 97 citations

Base Analog and Neighboring Base Effects on Substrate Specificity of Recombinant Human G:T Mismatch-Specific Thymine DNA−Glycosylase

1996 • 97 citations

DNA glycosylases

1997 • 87 citations

Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR.

1993 • 86 citations

Base Excision Repair of DNA Damage

1999 • 84 citations

Reconstitution of Human Base Excision Repair with Purified Proteins

1997 • 84 citations

Cell cycle regulation andin vitrohybrid arrest analysis of the major human uracil-DNA glycosylase

1991 • 71 citations

Quantitative MALDI-TOF MS of oligonucleotides and a nuclease assay

1996 • 71 citations

Small pool expression screening: Identification of genes involved in cell cycle control, apoptosis, and early development

1997 • 67 citations

Cloning of Mix-related homeodomain proteins using fast retrieval of gel shift activities, (FROGS), a technique for the isolation of DNA-binding proteins

1998 • 55 citations

Purification and Biochemical Characterization of Recombinant N-Methylpurine-DNA Glycosylase of the Mouse

1994 • 51 citations

Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor

1995 • 50 citations

Affinity Purification and Comparative Analysis of Two Distinct Human Uracil-DNA Glycosylases

1996 • 40 citations

An Improved Method for The Preparation Of The Phosphoramidites Of Modified 2′-Deoxynucleotides: Incorporation Of 8-Oxo-2′-Deoxy-7<u>H</u>-Guanosine Into Synthetic Oligomers

1991 • 38 citations

The effects of N7-methylguanine on duplex DNA structure

1994 • 36 citations

Kinetics of Oxidized Cytosine Repair by Endonuclease III of Escherichia coli

1997 • 32 citations

Synthesis and Characterization of DNA Fragments Bearing an Adenine Radiation Product: 7,8‐Dihydroadenin‐8‐one

1988 • 29 citations

1,N⁶-etheno deoxy and ribo adenoGine and 3,N⁴-etheno deoxy and ribo cytidine phosphoramidites. Strongly fluorescent structures for selective introduction in defined sequence DNA and RNA molecules

1994 • 28 citations

Solid-phase synthesis of DNA fragments containing the modified base 7-hydro-8-oxo-2′-deoxyguanosine

1991 • 26 citations

Use of an oocyte expression assay to reconstitute inductive signaling.

1995 • 20 citations

Chemical approaches toward understanding base excision DNA repair

1997 • 14 citations