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Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

Data up to Jan 2025

Published1995
Citations259
References51

Total Citations Per Year

Abstract

References (51)

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1977 • 513 citations

A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase.

1991 • 332 citations

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.

1977 • 265 citations

The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells.

1993 • 216 citations

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.

1989 • 183 citations

Specific mutator effects of ung (uracil-DNA glycosylase) mutations in Escherichia coli

1982 • 179 citations

Uracil DNA-glycosylase from HeLa cells: general properties, substrate specificity and effect of uracil analogs

1981 • 171 citations

Improved mountant for immunofluorescence preparations.

1974 • 161 citations

Efficient removal of uracil from G.U mispairs by themismatch-specific thymine DNA glycosylase from HeLa cells.

1994 • 146 citations

Nuclear and mitochondrial forms of human uracil-DNA glycosylase are encoded by the same gene

1993 • 134 citations

Uracil DNA-glycosylase. Purification and properties of this enzyme isolated from blast cells of acute myelocytic leukemia patients.

1980 • 112 citations

The presence of nuclear and mitochondrial uracil-DNA glycosylase in extracts of human KB cells.

1980 • 109 citations

Sequence analysis, expression, and conservation of Escherichia coli uracil DNA glycosylase and its gene (ung).

1988 • 107 citations

Interindividual variation in the activity of O6-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs

1983 • 102 citations

The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair

1991 • 101 citations

Formation of Okazaki fragments in polyoma DNA synthesis caused by misincorporation of uracil

1978 • 96 citations

Consensus sequences for good and poor removal of uracil from double stranded DNA by uracil-DNA glycosylase

1993 • 81 citations

Molecular cloning and primary structure of the uracil-DNA-glycosylase gene from Saccharomyces cerevisiae

1989 • 77 citations

Purification and properties of mitochondrial uracil-DNA glycosylase from rat liver

1988 • 73 citations

Cell cycle regulation andin vitrohybrid arrest analysis of the major human uracil-DNA glycosylase

1991 • 71 citations

Destabilization of messenger RNA/complementary DNA duplexes by the elongating 80 S ribosome.

1986 • 70 citations

Accumulation of small fragments of DNA in isolated HeLa cell nuclei due to transient incorporation of dUMP

1978 • 68 citations

Stimulation of the nuclear uracil DNA glycosylase in proliferating human fibroblasts.

1981 • 67 citations

A human enzyme that liberates uracil from DNA

1976 • 64 citations

Identification of the coding sequence for herpes simplex virus uracil-DNA glycosylase

1988 • 61 citations

Processivity of uracil DNA glycosylase

1993 • 58 citations

Repair of premutagenic DNA lesions in human fetal tissues: evidence for low levels of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase activity in some tissues

1983 • 56 citations

Isolation and characterization of a human cDNA encoding uracil-DNA glycosylase

1991 • 50 citations

Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase.

1993 • 48 citations

Isolation and characterization of monoclonal antibodies directed against the DNA repair enzyme uracil DNA glycosylase from human placenta.

1983 • 41 citations

Properties of purified uracil-DNA glycosylase from calf thymus. An in vitro study using synthetic DNA-like substrates.

1982 • 38 citations

Isolation and characterization of the human uracil DNA glycosylase gene.

1989 • 36 citations

Uracil-DNA glycosylases preferentially excise mispaired uracil

1992 • 34 citations

Excision of uracil residues in DNA: mechanism of action ofEscherichia coliandMicrococcus luteusuracil-DNA glycosylases

1985 • 34 citations

Purification and determination of the amino-terminal amino acid sequence of uracil-DNA glycosylase from human placenta

1989 • 31 citations

Uracil-DNA glycosylase in HeLa S3 cells: interconvertibility of 50 and 20 kDa forms and similarity of the nuclear and mitochondrial form of the enzyme

1985 • 29 citations

Nucleotide sequence of theStreptococcus pneumoniae unggene encoding uracil-DNA glycosylase

1990 • 19 citations

Expression of O6-methylguanine-DNA methyltransferase and uracil-DNA glycosylase in human placentae from smokers and non-smokers

1992 • 14 citations

Purification of the human O6‐methylguanine‐DNA methyltransferase and uracil‐DNA glycosylase, the latter to apparent homogeneity

1988 • 11 citations

Intracellular Localization of Rat‐Liver Uracil‐DNA Glycosylase

1983 • 10 citations

Characterization of the ung1 mutation ofEscherichia coli

1989 • 8 citations

Deleted Work

1955 • 0 citations

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Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence… (1995) – Biochemistry | Metascience Observatory Explorer