Normal human dermal fibroblasts: Proteomic analysis of cell layer and culture medium

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels

1980 • 3,334 citations

The current state of two-dimensional electrophoresis with immobilized pH gradients

2000 • 1,498 citations

Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity

2001 • 1,207 citations

Connective Tissue and Its Heritable Disorders

2002 • 930 citations

New Goals for the U.S. Human Genome Project: 1998-2003

1998 • 848 citations

Improvement of an "In-Gel" Digestion Procedure for the Micropreparation of Internal Protein Fragments for Amino Acid Sequencing

1995 • 755 citations

Mechanisms of Myofibroblast Activity and Phenotypic Modulation

1999 • 580 citations

The Proteasome, a Novel Protease Regulated by Multiple Mechanisms

1999 • 540 citations

Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

2000 • 531 citations

Vertebrate tropomyosin: distribution, properties and function.

2001 • 457 citations

A nonlinear wide‐range immobilized pH gradient for two‐dimensional electrophoresis and its definition in a relevant pH scale

1993 • 386 citations

YPDTM, PombePDTM and WormPDTM: model organism volumes of the BioKnowledgeTM Library, an integrated resource for protein information

2001 • 329 citations

Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining

1988 • 305 citations

Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer

2002 • 291 citations

Protein expression profiles in human breast ductal carcinoma and histologically normal tissue

1997 • 286 citations

Protein identification in the post-genome era: the rapid rise of proteomics

1997 • 270 citations

Extracellular Matrix and Cytokines: A Functional Unit

2000 • 265 citations

Inside SWISS‐2DPAGE database

1995 • 229 citations

Proteomics: a new approach to the study of disease

2000 • 205 citations

Maneuvering in the Complex Path from Genotype to Phenotype

2002 • 188 citations

Functional Proteomics Analysis of Signal Transduction Pathways of the Platelet-Derived Growth Factor β Receptor

1999 • 183 citations

The Myofibroblast: An Assessment of Controversial Issues and a Definition Useful in Diagnosis and Research

2001 • 182 citations

An evaluation of the use of two-dimensional gel electrophoresis in proteomics

2001 • 149 citations

Mitochondrial-matrix proteins at unexpected locations: are they exported?

1999 • 148 citations

Protein identification in DNA databases by peptide mass fingerprinting

1994 • 131 citations

Molecular genetics of pseudoxanthoma elasticum: a metabolic disorder at the environment–genome interface?

2001 • 124 citations

ENDOTHELIAL CELLS IN CULTURE: A MODEL FOR STUDYING VASCULAR FUNCTIONS

2000 • 116 citations

The current status of primary hepatocyte culture

1998 • 113 citations

Fibronectin fragments and their role in inflammatory arthritis

2000 • 111 citations

Approach to stationary two‐dimensional pattern: Influence of focusing time and Immobiline/carrier ampholytes concentrations

1988 • 105 citations

Nonmuscle and smooth muscle myosin light chain mRNAs are generated from a single gene by the tissue-specific alternative RNA splicing.

1987 • 97 citations

Proteomic analysis

2000 • 82 citations

Human 2‐D PAGE databases for proteome analysis in health and disease: http ://biobase.dk/cgi‐bin/celis

1996 • 77 citations

Human liver protein map: Update 1993

1993 • 75 citations

Protein-protein interaction of FHL3 with FHL2 and visualization of their interaction by green fluorescent proteins (GFP) two-fusion fluorescence resonance energy transfer (FRET)

2000 • 72 citations

Connective tissue cells, cell proliferation and synthesis of extracellular matrix — a review

1975 • 70 citations

The MRC‐5 human embryonal lung fibroblast two‐dimensional gel cellular protein database: Quantitative identification of polypeptides whose relative abundance differs between quiescent, proliferating and SV 40 transformed cells

1990 • 67 citations

The Human Genome Project: Reaching the Finish Line

1998 • 67 citations

Vertebrates have conserved capping protein α isoforms with specific expression patterns

1997 • 62 citations

Tissue Repair and Regeneration

1982 • 57 citations

A Proteomic Approach to the Identification of Lung Cancer Markers

2001 • 56 citations

Standardized characterization of gene expression in human colorectal epithelium by two‐dimensional electrophoresis

1997 • 53 citations

Overexpression of human fibroblast caldesmon fragment containing actin-, Ca++/calmodulin-, and tropomyosin-binding domains stabilizes endogenous tropomyosin and microfilaments.

1994 • 51 citations

The Proteasome Subunit, C2, Contains an Important Site for Binding of the PA28 (11S) Activator

1996 • 50 citations

Interactions of fibroblasts with the extracellular matrix: implications for the understanding of fibrosis

1999 • 39 citations

Proteomics — the protein expression technology to study connective tissue biology

2001 • 37 citations

A proteomic approach to mimic fibrosis disease evolvement by anin vitro cell line

2001 • 35 citations

Monitoring of Gene Expression by Functional Proteomics: Response of Human Lung Fibroblast Cells to Stimulation by Endothelin-1

2001 • 34 citations

Proteomics and its impact upon biomedical science

2002 • 31 citations

Restricted access chromatographic sample preparation of low mass proteins expressed in human fibroblast cells for proteomics analysis

2001 • 27 citations

Contractile events during inflammation

1976 • 23 citations

Proteomic analysis of human skin fibroblasts grown on titanium: Novel approach to study molecular biocompatibility

2001 • 21 citations

Genome- and proteome-based technologies: status and applications in the postgenomic era

2001 • 17 citations

Combined genome and proteome approach to identify new susceptibility genes

2002 • 13 citations

Primary skin fibroblasts as human model system for proteome analysis

2002 • 11 citations