Protein interactions of homeodomain proteins

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

HOMEODOMAIN PROTEINS

1994 • 828 citations

Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions

1991 • 538 citations

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

1994 • 506 citations

The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: Comparison with prokaryotic repressors

1989 • 468 citations

Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

1990 • 460 citations

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.

1995 • 396 citations

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

1995 • 391 citations

Cooperative dimerization of paired class homeo domains on DNA.

1993 • 380 citations

The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

1994 • 378 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

1995 • 355 citations

Structure of serum response factor core bound to DNA

1995 • 340 citations

Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations

1995 • 325 citations

Evolution of homeobox genes

2012 • 283 citations

Pbx Modulation of Hox Homeodomain Amino-Terminal Arms Establishes Different DNA-Binding Specificities across theHoxLocus

1996 • 274 citations

Determination of the Nuclear Magnetic Resonance Solution Structure of an Antennapedia Homeodomain-DNA Complex

1993 • 270 citations

extradenticle Raises the DNA binding specificity of homeotic selector gene products

1994 • 269 citations

Crystal Structure of the MATa1/MATα2 Homeodomain Heterodimer Bound to DNA

1995 • 260 citations

Cooperative Interactions between HOX and PBX Proteins Mediated by a Conserved Peptide Motif

1995 • 224 citations

The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins.

1994 • 207 citations

The Pentapeptide Motif of Hox Proteins Is Required for Cooperative DNA Binding with Pbx1, Physically Contacts Pbx1, and Enhances DNA Binding by Pbx1

1995 • 167 citations

Both Pbx1 and E2A-Pbx1 Bind the DNA Motif ATCAATCAA Cooperatively with the Products of Multiple Murine Hox Genes, Some of Which Are Themselves Oncogenes

1995 • 146 citations

Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction.

1995 • 122 citations

A short, disordered protein region mediates interactions between the homeodomain of the yeast α2 protein and the MCM1 protein

1993 • 120 citations

Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity.

1995 • 115 citations

Structural Determinants within Pbx1 That Mediate Cooperative DNA Binding with Pentapeptide-Containing Hox Proteins: Proposal for a Model of a Pbx1-Hox-DNA Complex

1996 • 110 citations

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.

1996 • 108 citations

The hexapeptide LFPWMR in Hoxb-8 is required for cooperative DNA binding with Pbx1 and Pbx2 proteins.

1995 • 104 citations

Nuclear Magnetic Resonance Solution Structure of the fushi tarazu Homeodomain from Drosophila and Comparison with the Antennapedia Homeodomain

1994 • 73 citations

MCM1 point mutants deficient in expression of alpha-specific genes: residues important for interaction with alpha 1.

1994 • 61 citations

Secondary structure of the homeo domain of yeast alpha 2 repressor determined by NMR spectroscopy.

1991 • 57 citations

37 A Combinatorial Regulatory Circuit in Budding Yeast

1992 • 53 citations

Altered DNA Recognition and Bending by Insertions in the α2 Tail of the Yeast a1/α2 Homeodomain Heterodimer

1995 • 48 citations

The Yeast α2 and Mcm1 Proteins Interact through a Region Similar to a Motif Found in Homeodomain Proteins of Higher Eukaryotes

1996 • 47 citations

The Swi5 zinc-finger and Grf10 homeodomain proteins bind DNA cooperatively at the yeast HO promoter.

1993 • 42 citations