Isoalloxazine derivatives promote photocleavage of natural RNAs at G.U base pairs embedded within helices

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

The RNA world

1986 • 1,961 citations

Mapping adenines, guanines, and pyrimidines in RNA

1977 • 1,391 citations

Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing

1996 • 1,240 citations

Inorganic Biochemistry

1974 • 834 citations

Comparative and functional anatomy of group II catalytic introns — a review

1989 • 768 citations

PSORALENS AS PHOTOACTIVE PROBES OF NUCLEIC ACID STRUCTURE AND FUNCTION: ORGANIC CHEMISTRY, PHOTOCHEMISTRY, AND BIOCHEMISTRY

1985 • 749 citations

Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective

1994 • 673 citations

Cloning and expression of the gene for bacteriophage T7 RNA polymerase.

1984 • 665 citations

Crystallographic refinement of yeast aspartic acid transfer RNA

1985 • 498 citations

Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses

1984 • 477 citations

PHOTODYNAMIC THERAPY OF MALIGNANT TUMOURS

1972 • 405 citations

Crystal structure of yeast phenylalanine transfer RNA

1978 • 375 citations

RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity

1996 • 361 citations

8-Hydroxydeoxyguanosine formation at the 5' site of 5'-GG-3' sequences in double-stranded DNA by UV radiation with riboflavin

1993 • 298 citations

Water: An Integral Part of Nucleic Acid Structure

1988 • 280 citations

Structure of yeast phenylalanine transfer RNA at 2.5 A resolution.

1975 • 278 citations

The Science of Photobiology

1989 • 257 citations

Further refinement of the structure of yeast tRNAPhe

1978 • 243 citations

Intervening sequence in the thymidylate synthase gene of bacteriophage T4.

1984 • 203 citations

New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing

1986 • 189 citations

Long-range oxidation of guanine by Ru(III) in duplex DNA

1997 • 188 citations

Nuclease activity of 1,10-phenanthroline-copper ion: reaction with CGCGAATTCGCG and its complexes with netropsin and EcoRI

1986 • 173 citations

Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals

1988 • 159 citations

Minor Groove Recognition of the Conserved G⋅U Pair at the Tetrahymena ribozyme Reaction Site

1995 • 156 citations

RNA hydration: three nanoseconds of multiple molecular dynamics simulations of the solvated tRNA Asp anticodon hairpin 1 1Edited by J. Karn

1997 • 155 citations

Specificity for Aminoacylation of an RNA Helix: an Unpaired, Exocyclic Amino Group in the Minor Groove

1991 • 148 citations

Phototherapeutic potential of alternative photosensitizers to porphyrins

1994 • 136 citations

RNA‐protein interactions

1995 • 113 citations

Catalytic Role of 2′-Hydroxyl Groups Within a Group II Intron Active Site

1996 • 104 citations

Monitoring of the Cooperative Unfolding of the sunY Group I Intron of Bacteriophage T4

1993 • 101 citations

H-bond stability in the tRNA(Asp) anticodon hairpin: 3 ns of multiple molecular dynamics simulations

1996 • 80 citations

RNA-protein interactions

1991 • 71 citations

Dissection of the Role of the Conserved G.cntdot.U Pair in Group I RNA Self-Splicing

1994 • 69 citations

Replacement of the Conserved G.cntdot.U with a G-C Pair at the Cleavage Site of the Tetrahymena Ribozyme Decreases Binding, Reactivity, and Fidelity

1994 • 68 citations

The environment of two metal ions surrounding the splice site of a group I intron.

1996 • 67 citations

RNA-protein interactions

1992 • 65 citations

Hydroxyl radical cleavage of tRNA in the ribosomal P site.

1992 • 61 citations

Genetic Delineation of Functional Components of the Group I Intron in the Phage T4 td Gene

1987 • 56 citations

Photooxidation of d(TpG) by phthalocyanines and riboflavin. Isolation and characterization of dinucleoside monophosphates containing the 4R^*and 4S^*d iastereoisomers of 4,8-di hyd ro-4-hydroxy-8-oxo-2′-deoxyguanosine

1992 • 49 citations

Recognition of G-U mismatches by tris(4,7-diphenyl-1,10-phenanthroline)rhodium(III)

1992 • 48 citations

Lead cleavage sites in the core structure of group I intron-RNA

1993 • 47 citations

Cleavage of tRNA by Fe(II)-bleomycin.

1992 • 37 citations

Effects of mutations of the bulged nucleotide in the conserved P7 pairing element of the phage T4 td intron on ribozyme function

1991 • 26 citations

Neocarzinostatin acts as a sensitive probe of DNA microheterogeneity: switching of chemistry from C-1' to C-4' by a G.T mismatch 5' to the site of DNA damage.

1992 • 26 citations

Determination of nucleotide distances in RNA by means of copper phenanthroline-generated hydroxyl radical cleavage pattern.

1995 • 24 citations

Specific function of a G.U wobble pair from an adjacent helical site in tRNA(Ala) during recognition by alanyl-tRNA synthetase.

1996 • 22 citations

Poly(pyrrolecarboxamides) linked to photoactivable chromophore isoalloxazine. Synthesis, selective binding, and DNA cleaving properties

1994 • 17 citations

Sequence-directed single strand cleavage of DNA by a netropsin-flavin hybrid molecule

1995 • 11 citations